Translational Research in Asthma
Anurag Agrawal combines his early training in medicine and interest in research to study the molecular basis of asthma and other respiratory disorders. His interests range from mechanistic studies in animal models of asthma to a computational approach based systems view of the disease.
He aims to develop better diagnostic tools for early detection of asthma; to create better drugs; and better strategies for individualized medicine.
He is the coordinator of a CSIR Centre of Excellence for Translational Research in Asthma & Lung disease (TRiAL), as well as the Indo-US Centre of Excellence for Environmental Lung Diseases (with Johns Hopkins University, USA, and Chest Research Foundation, India).
- Emerging Interface Between Metabolic Syndrome And Asthma. Agrawal A*, Mabalirajan U, Ahmad T, Ghosh B. Am J Respir Cell Mol Biol. 2011 (in-press).
- Simvastatin Improves Epithelial Dysfunction and Airway Hyperresponsiveness: From ADMA to Asthma. Ahmad T, Mabalirajan U, Sharma A, Aich J, Makhija L, Ghosh B, Agrawal A*. Am J Respir Cell Mol Biol. 2011 (in-press)
- Beneficial effects of high dose of L-Arginine on airway hyperresponsiveness and airway inflammation in a murine model of asthma. Mabalirajan U, Ahmad T, Leishangthem GD, Duraisamy AJ, Dinda AK, Agrawal A, Ghosh B*. J Allergy Clin Immunol. 2010. 125(3):626-35.
- Altered Asymmetric Dimethyl Arginine metabolism in allergically inflamed mice lungs. Ahmad T, Mabalirajan U, Ghosh B, and Agrawal A*. Am J Resp Cell Mol Biol. 2010. 42(1):3-8.
- Posttranscriptional regulation of interleukin-10 expression by hsa-miR-106a. Sharma, A., Kumar, M., Aich, J., Hariharan, M., Brahmachari, S. K., Agrawal, A., and Ghosh, B*. Proc.Natl.Acad.Sci.U.S.A. 2009. 106, 5761-5766.