V. C. Kalia works in the area of environmental biotechnology where the focus is on how microbes can be used as a resource for the generation of bioenergy and other bioproducts.
His major interests are in:
Identification of microorganisms as genetic reservoirs for the generation of hydrogen
Potential bio-transformations of polyhydroxybutyrate biosynthesis pathway through comparative genomics
His group has made significant advances in using different bacillus strains for the production of polyhydroxybutyrate, a key molecule in the development of bioplastics. He and his group have also used genomic and metabolic databases to identify hydrogen producers from a large number of sequenced genomes of microorganisms.
- Quenching the quorum sensing system: potential antibacterial drug targets. Kalia, V.C., Purohit, H.J. 2011 Critical Review Microbiol 37(2):121-140
- Phylogeny in aid of the present and novel microbial lineages: diversity in Bacillus. Porwal, S., Lal, S., Cheema, S., and Kalia, V. C. PLoS.One. 2009. 4, e4438.
- Hydrogen and polyhydroxybutyrate producing abilities of microbes from diverse habitats by dark fermentative process. Porwal, S., Kumar, T., Lal, S., Rani, A., Kumar, S., Cheema, S., Purohit, H. J., Sharma, R., Singh Patel, S. K., and Kalia, V. C. Bioresour.Technol. 2008. 99, 5444-5451.
- Genomic databases yield novel bioplastic producers. Kalia, V. C., Chauhan, A., Bhattacharyya, G., and Rashmi. Nat.Biotechnol. 2003. 21, 845-846.
- Analysis of the unexplored features of rrs (16S rDNA) of the genus Clostridium. Kalia, V.C., Mukherjee, T., Bhushan, A., Joshi, J., Shankar, P., Huma, N. 2011 BMC Genomics 12:18