Research Highlights

Posttranscriptional regulation of interleukin-10 expression by hsa-miR-106a.
Sharma A, Kumar M, Aich J, Hariharan M, Brahmachari SK, Agrawal A, Ghosh B.
Proc Natl Acad Sci U S A. 2009;106:5761-6.

Mechanistic and functional insights into fatty acid activation in Mycobacterium tuberculosis.
Arora P, Goyal A, Natarajan VT, Rajakumara E, Verma P, Gupta R, Yousuf M, Trivedi OA, Mohanty D, Tyagi A, Sankaranarayanan R, Gokhale RS.
Nat Chem Biol. 2009 5:166-73.

Genetic landscape of the people of India: a canvas for disease gene exploration.
Indian Genome Variation Consortium.
J Genet. 2008;87:3-20.

FishMap: a community resource for zebrafish genomics.
Meli R, Prasad A, Patowary A, Lalwani MK, Maini J, Sharma M, Singh AR, Kumar G, Jadhav V, Scaria V, Sivasubbu S.
Zebrafish. 2008;5:125-30.

Inhibition of translation in living eukaryotic cells by an RNA G-quadruplex motif.
Arora A, Dutkiewicz M, Scaria V, Hariharan M, Maiti S, Kurreck J.
RNA. 2008;14:1290-6.

Perspectives on chemistry and therapeutic applications of Locked Nucleic Acid (LNA).
Kaur H, Babu BR, Maiti S.
Chem Rev. 2007;107:4672-97.

Genome-wide prediction of G4 DNA as regulatory motifs: role in Escherichia coli global regulation.
Rawal P, Kummarasetti VB, Ravindran J, Kumar N, Halder K, Sharma R, Mukerji M, Das SK, Chowdhury S.
Genome Res. 2006;16:644-55.

Polyethylenimine nanoparticles as efficient transfecting agents for mammalian cells.
Nimesh S, Goyal A, Pawar V, Jayaraman S, Kumar P, Chandra R, Singh Y, Gupta KC.
J Control Release. 2006;110:457-68.

Targets for human encoded microRNAs in HIV genes.
Hariharan M, Scaria V, Pillai B, Brahmachari SK.
Biochem Biophys Res Commun. 2005;337:1214-8.

Assessing natural variations in gene expression in humans by comparing with monozygotic twins using microarrays.
Sharma A, Sharma VK, Horn-Saban S, Lancet D, Ramachandran S, Brahmachari SK.
Physiol Genomics. 2005;21:117-23

Dissecting the mechanism and assembly of a complex virulence mycobacterial lipid.
Trivedi OA, Arora P, Vats A, Ansari MZ, Tickoo R, Sridharan V, Mohanty D, Gokhale RS.
Mol Cell. 2005;17:631-43.

Alu repeat analysis in the complete human genome: trends and variations with respect to genomic composition.
Grover D, Mukerji M, Bhatnagar P, Kannan K, Brahmachari SK.
Bioinformatics. 2004;20:813-7.

Enzymic activation and transfer of fatty acids as acyl-adenylates in mycobacteria.
Trivedi OA, Arora P, Sridharan V, Tickoo R, Mohanty D, Gokhale RS.
Nature. 2004;428:441-5.

A new family of type III polyketide synthases in Mycobacterium tuberculosis.
Saxena P, Yadav G, Mohanty D, Gokhale RS.
J Biol Chem. 2003;278:44780-90.

Nonrandom distribution of alu elements in genes of various functional categories: insight from analysis of human chromosomes 21 and 22.
Grover D, Majumder PP, B Rao C, Brahmachari SK, Mukerji M.
Mol Biol Evol. 2003;20:1420-4.

Polyhydroxyalkanoates: an overview.
Reddy CS, Ghai R, Rashmi, Kalia VC.
Bioresour Technol. 2003;87:137-46.

CAG repeat instability at SCA2 locus: anchoring CAA interruptions and linked single nucleotide polymorphisms.
Choudhry S, Mukerji M, Srivastava AK, Jain S, Brahmachari SK.
Hum Mol Genet. 2001;10:2437-46.

Molecular analysis of autosomal dominant hereditary ataxias in the Indian population: high frequency of SCA2 and evidence for a common founder mutation.
Saleem Q, Choudhry S, Mukerji M, Bashyam L, Padma MV, Chakravarthy A, Maheshwari MC, Jain S, Brahmachari SK.
Hum Genet. 2000;106:179-87.