|
Prof. Samir K. Brahmachari
skb@igib.res.in
Director,
Institute of Genomics and
Integrative Biology.
(formerly Centre for Biochemical Technology)
Principal Investigator: Programme on
Functional Genomics @ IGIB, Delhi.
|
Name
:
PROF. SAMIR K. BRAHMACHARI
Date of Birth
: 1st January 1952
Present Position
: Director
Institute of Genomics & Integrative Biology (CSIR)
Mall Road, Delhi Univ.
Campus,
Delhi 110 007
Phone
: 91-11-2766 7298, 2766 7578
Fax
:
91-11-2766 7471, 2766 2407-8
Academic Record
Degree
Subject
Year University
Ph.D. Molecular
Biophysics 1978
Indian Institute of Science,
Bangalore
M.Sc. Pure
Chemistry 1973-74
University of Calcutta
(Physical Chemistry
Specialisation)
B.Sc. Chemistry (Hons.)
1971-72 University of Calcutta
Professional Appointments
Positions Held
Period
Name of Organization
Director 11th
August 1997-Present
Institute of Genomics & Integrative Biology,
CSIR, Delhi
Professor
June 1997 - Aug 2003
Molecular Biophysics Unit, Indian
Institute
of Science, Bangalore
Associate Professor April
1992-June1997 Molecular Biophysics
Unit, Indian Institute
of Science, Bangalore
Visiting Professor May-July
1997 Max. Planck Institute
of Biophysical Chemistry,
Goettingen,
Germany
Associated Faculty April
1989-March 1995 Centre for Genetic
Engineering, Indian
Institute of Science, Bangalore.
Asst. Professor April
1986 - March 1992 Molecular Biophysics
Unit, Indian Institute
of Science,
Bangalore
Lecturer April
1981 - March 1986 Molecular Biophysics
Unit, Indian Institute
of Science, Bangalore
Research Associate Dec
1979-March 1981 Molecular Biophysics
Unit, Indian Institute
of Science, Bangalore
Visiting
Scientist Nov. 1979
Dept of Biochemistry, Memorial
University
of Newfoundland, St. Jones,
Newfoundland,
Canada
Post-Doctoral Sept.
1978-Oct.1979 French Govt.
fellowship Institute, de
Rechercheen Biologie Moleculaire
CNRS, Univ. of Paris, Paris VII
Adjunct Professor June
2003-Present Bioinformatics
Centre
University
of Pune, Pune
Visiting Professor Jan
1998-Present B. R. Ambedkar
Centre for
Biomedical Research,
University of Delhi, Delhi
Awards and Honours
Name of
Award
Conferring
Agency
Year
-
National Science Talent
NCERT
(INDIA)
1968
Search
Scholarship
-
Young scientist medal
Indian National Science
Academy 1979
-
Kani
medal
National Cancer Research
Centre, 1981
Tokyo, Japan
-
Cama Memorial Award
Society of Biological Chemists
(India) 1990
-
Shanti Swarup Bhatnagar
Council of Scientific & Industrial
Research 1990
Award in
Biological Sciences (India)
-
C.
R. Krishnamurthy
Society of Biological Chemists
(India) 1998
Oration
Award
-
FICCI Award 1998-99 in Federation
of Indian Chambers of 1999
recognition
of individual initiative Commerce and
Industry
in Life
Sciences including agriculture
-
Millennium Medal
Indian Science
Congress 2000
-
Ranbaxy Research Award
Ranbaxy Science Foundation
2002
for The Year
2001 in the field
of “Medical
Sciences – Medical
Research”
·
Goyal Prize 2001 in the field of Kurukshetra
University
2003
Life
Sciences.
-
B.
K. Bachhawat Oration
JNU
2003
Lecture
Award
-
C.
R. Krishnamurthy
CDRI
2003
Oration
Award
-
Prof. P.K. Bose
Memorial Award Indian Chemical
Society 2004
-
Dr. B.R.
Ambedkar Centenary Award Indian Council of
Medical Research 2005
for excellence in biomedical research
-
The Jagadis
Chandra Bose Medal Indian National
Science Academy 2007
-
H. K. Firodia
Awards For Excellence H.K. Firodia
Memorial Foundation 2007
In
Science and Technology
Membership/Fellowships to Academies
and Scientific Bodies
-
Elected
member Guha
Research conference
(India) 1986
-
Fellowship of the
Indian Indian Academy
of Sciences 1991
Academy of
Sciences
-
Elected
member Human
Genome Organization (HUGO) 1991
-
Fellowship of the
Indian Indian National
Science Academy 1995
National
Science Academy
-
Elected Council Member
Federation of Asian & Oceanic
1995
Biochemistry
and Molecular Biology
-
Fellowship of the National
National Academy of
Sciences 2001
Academy of
Sciences, Allahabad
-
Elected Council
Member, HUGO Human Genome Organisation
(HUGO) 2004
·
Fellow of Biotech Research
Biotech Research Society of India
2005
Society of India
(BRSI) (BRSI), RRL,
Trivandrum
Membership of Professional Bodies,
Organization of Conferences, etc.
·
National Responsibilities
1.
Organizing Secretary,
International symposium on Biomolecular Structure
and Interactions, Dec 1984.
2.
Invited member,
“Advisory Committee to Curriculum Development Centre
for Postgraduate Education in Biophysics”. India
1987-1988.
3.
General Secretary,
Society of Biological Chemists, India, 1987-89,
1993-95.
4.
Executive committee
member, Society of Biological Chemists, India, 1987.
5.
Convenor, INDO-SOVIET
Workshop on “DNA Protein Interaction & Crosslinking”
Bangalore, March 1990.
6.
Member, Task Force on
Medical Biotechnology, Dept. of Biotechnology,
Government of India. 1990-’94.
7.
Member, Editorial
Board, Journal of Biosciences 1991-97.
8.
Member, Chemical
Sciences and Technology Research Committee, CSIR
(India) 1993-98.
9.
Convenor, Review
meeting on “Trends in DNA Structure-Function and
Genome Organization”, Bangalore, Jan 1993.
10.
Member, Task Force on
Human Genetics, Dept. of Biotechnology, Government
of India. 1994.
11.
Member, National
Organizing Committee, XVI IUBMB Congress, New Delhi,
September 1994.
12.
Member, National
Organizing Committee, Third Asian Conference on
Transcription, Bangalore, September 1994.
13.
Member, National
Bioethics Committee, Ministry of Science &
Technology, Department of Biotechnology, w.e.f.
November 1999- 15 November, 2006.
14.
Member, Animal Ethics
Committee, Delhi University South Campus.
15.
Member, Management
Council, Institute of Microbial Technology,
Chandigarh.
16.
Member, Research
Council, National Institute of Science, Technology
and Development Studies, New Delhi.
17.
Member Academic
Committee, National Institute of Immunology, New
Delhi.
18.
Member Advisory
Committee of the Biotechnology Teaching Programme,
Ambedkar Centre for Biomedical Research, Delhi.
19.
Member, Society,
Governing Body, and Finance Committee, National
Brain Research Centre, New Delhi.
20.
Member, Board of
Governors, National Institute of Pharmaceutical
Education & Research, Punjab.
21.
Member, Sectional
Committee-IX of Indian National Science Academy. -
INSA Medal for Young Scientists, New Delhi.
22.
Member, Performance
Appraisal Board, Council of Scientific & Industrial
Research, New Delhi.
23.
Member, Advisory
Committee, CSIR Young Scientists Award on Biological
Sciences for the year 2000, New Delhi.
24.
Chairman, Research
Advisory Committee, National Bureau of Animal
Genetic Resources, Karnal (Haryana).
25.
Member, Research
Council, Centre for Cellular and Molecular Biology,
Hyderabad, 2001 - 2007
26.
Member, Research
Council, Central Drug Research Institute, Lucknow,
2004-2007.
27.
Visitor’s nominee,
Selection committee for teaching post, Centre for
Molecular Medicine, Jawaharlal Nehru University, New
Delhi.
28.
Member, Governing body
and Society, Council of Scientific & Industrial
Research for a period of three years, 2001-2004.
29.
Member, Recombinant
Drug advisory Panel, Ministry of Health and Family
welfare, Govt. of India.
30.
Member, Task Force Madhya Pradesh Expert Committee
for Life Sciences.
31.
Member, Maharashtra Biotech Commission.
32.
Member, Kelkar high power Committee of CSIR.
33.
Member, Task Force Himachal Pradesh.
34.
Area Coordinator (Life Sciences)
Integrated Long Term Programme (ILTP), Department of
Science and Technology, New Delhi.
35.
Appointed Chairman of Project Advisory Committee for
International Programmes in Life Sciences &
Biotechnology (PAC-LSBT), Department of Science &
Technology, Govt. of India, w.e.f. 25th
January, 2005.
36.
Chairman, Working Group on Bioinformatics Research
and Development, Ministry of Communication and
Information Technology (DIT), Govt. of India, 7th
October 2005- Present.
37.
Member, Medical Biotechnology Development Board,
Ministry of S&T, Department of Biotechnology, India
w.e.f. 15th July, 2005.
38.
Member, Steering Committee on Technology Financing
in India – A National Initiative, Department of
Science & Technology, India w.e.f. July 2004.
39.
Member, CSIR Working Group for the formulation of XI
th Five
Year Plan w.e.f. December, 2005.
40.
Chairman, CSIR Committee for “Optimising the CSIR
support staff in various streams in the global
context”.
41.
Member, CSIR Change Team for the
implementation of recommendation of Kelkar
Committee.
42.
Member, Indian Council of medical
Research (ICMR) for preparing the XI th
Five Year Plan document.
43.
Member, Advisory Committee of Special Centre for
Molecular Medicine, Jawaharlal Nehru University, New
Delhi, April 2006.
44.
Member, Committees for preparing plan and budget of
‘Biology & Biotechnology’ and ‘Drug, Pharma &
Healthcare’ Sectors of CSIR, India
·
International Responsibilities
1.
Council Member,
Federation of Asian & Oceanic Biochemistry and
Molecular Biology, 1995 till date.
2.
Advisory Board Member,
Journal of Biochemistry, Molecular Biology &
Biophysics. The official journal of FAOBMB.
3.
Chairman of the FAOBMB Fellowship
Committee for the 17th FAOBMB Symposium
“Genomics and Health for the 21st
Century” held at Thailand, November 2004.
4.
Chairman of the FAOBMB Fellowship
Committee for the 18th FAOBMB Symposium
“Genomics and Proteomics in Health and Agriculture”
held at Lahore, November 2005.
5.
Member, Human Genome
Organization 1991.
6.
Elected Member of the Human Genome
Organisation (HUGO) Council for the years 2004 to
2007.
7.
Member, Advisory group
on “Biotechnology & Human Rights” to H. R. High
Commission, Geneva.
8.
Member of India-European Commission S&T Steering
Committee responsible for Genomics & Biotechnology
for Health.
9.
Member, Planning Group of the Human Variome Project
coordinated by Professor Richard G. H. Cotton AM,
Director: Genomic Disorders Research Centre,
Melbourne, Australia, 2006.
10.
Appointed an independent Director on the Board of
the India Pharma Fund Ltd., an open-ended
multi-class investment company incorporated in
Mauritius in 2005.
11.
Coordinator of the Indo-EU workshop on “Functional
Genomics & Biotechnology for Health”, organized by
DST, India at Delhi on 27th and 28th April, 2005.
12.
Coordinator of the “Indo-Brazil-South Africa (IBSA)
Trilateral Workshop on "Functional Genomics, Life
Science, GM Food and Agriculture”, organized by DST,
India at Delhi on 18th -19th July, 2005.
13.
Coordinator of the “Indo-Taiwan Joint Workshop on
Functional Genomics” organized by DST, India at
Delhi on 20th-21st October, 2005.
14.
Organized the “2nd CSIR-NSFC Workshop on
Genome Informatics” at Delhi from 22nd to
25th February, 2006.
15.
Invited by the Council of Human Genome Organisation
to host the Human Genome Meeting in India in 2008
and to Chair the National Organising Committee .
16.
Regional Editor for South Asian Countries for the
Journal Genomic Medicine, 2006 onwards.
17.
Advisory Board member for Archon-X prize for
genomics, X-Prize foundation, USA.
Member of Important Delegation of
Govt. of India/ CSIR
1.
Member, Indian
delegation to attend 2nd Indo–US Round
Table Dialogue meeting in Washington DC, September
2000.
2.
Member, Indian
delegation to Moscow to explore the possibility of
bilateral co-operation with Russian Institutes in
the area of Biomedical Research, organised by
Department of Science & Technology, 6-12 October,
2002.
3.
Member, Indian
delegation to participate in the Indo-South African
Workshop on advanced computing, organised by
Department of Science & Technology at Pretoria, S.
Africa, 28-29 October, 2002.
4.
Member, Indian
delegation to London to participate in the `India
Day' celebrations on 11th December 2002
organised by the Royal Society, London.
5.
Member, Indian
delegation to Brussels to participate in the 1st
Meeting of the India-EC S&T Steering Committee
during March 3rd to 5th, 2004.
6.
Member, Indian
delegation to Russia for participation in the 12th
Session of ILTP Joint Council Meeting in St.
Petersburg and Joint Committee Meeting of the
Russian-Indian Centre for Ayurvedic Research in
Moscow from September 30 to October 4, 2004.
7.
Member of the Indian
delegation to Israel to attend the Workshop on
“Promoting and Facilitating Innovation driven new
ventures”, held from 29th May to 3rd
June, 2005 at Technion – Israel Institute of
Technology, Haifa, organised by TIFAC, DST.
8.
Lead a group of Indian
scientists to attend the Taiwan-India Joint
Symposium on Functional Genomics on 3rd-4th
March, 2006 at Taipei, Taiwan.
9.
Member, Indian
delegation to Brussels to participate in the 3rd
Meeting of the India-EC S&T Steering Committee
during November 16th-17th,
2006.
Research Achievements and Present
Research Interest
·
Major Scientific Achievements
Dr.
Brahmachari has demonstrated the structural
flexibility of DNA and the role of repetitive
sequences in DNA transactions much before the
discovery of repeats association with genetic
disorders. His work on the structural flexibility of
telomeric repeat sequences is one of his well cited
contributions. He has made major contributions in
molecular analysis of genetic disorders associated
with trinucleotide amplification and repetitive
sequence instability. Using a combination of
structural biology, computational genomics and
population based polymorphism scanning he and his
group have provided a novel structural frame work
for understanding the etiology of several
neurological disorders. He was first to establish a
close clinical network to address genetics of
complex disordres and demonstrated association of
two genes to Schizophrenia and Bipolar Disorder (synaptogyrin
1 and MLC1 gene) and identified several SNPs and
other markers associated to various neurological
disorders. Taking advantage of genetic diversity of
Indian population and core expertise in structural
biology and computation, he has pioneered functional
genomics initiative in India and and led the Indian
Genome Variation Consortium which developed a
database of over 1000 genes related to disease and
drug response, exploring human genome variation in
multi-ethnic, multi-lingual populations of India to
develop a national resource: the genetic profile of
the people of India.
Dr.
Brahmachari and coworkers have carried out extensive
computational analysis of the repetitive sequences
in the genome and were one of the first to propose
functional role of such sequence. He and his
associates have developed novel and unique tools for
genome annotation and identification of functional
signature for hypothetical proteins in the genome
through comparative genomics approach. He and his
group has developed novel softwares for genome
analysis and identified several novel non-active
site targets for bacterial pathogen under a national
network project in In Silico Biology for drug
target development led by him. He is also the first
to market novel globally competitive Bioinformatics
software products from CSIR. His group has also
developed tools for System Biology Platform. Recent
finding of Prof. Brahmachari and his associates that
Human miRNA can target critical genes in HIV, thus
preventing HIV proliferation has received wide
international recognition. (Petit-Zeeman, S. Nature
Rev. Drug Discovery, 2006, 5.5). His group has
developed computational model for gene-gene
interaction network for Complex Disorders like
schizophrenia.
Dr.
Brahmachari has also been involved in issues
relating to Human Genome research ethics and Human
Rights. As a member of the steering committee of the
International Human Rights Commission he has
contributed to the formulation of the draft
guidelines in terms of benefit sharing by the
populations that are the part of the research
endeavor as resources of genetic material and
addressed issues of unethical exploitation of
genetic resources of the Third world. His
contribution in India in promoting genomics research
through thrust area development in granting
agencies, lectures, courses and human-resource
training is very significant. Dr. Brahmachari has
contributed significantly in promoting
industry-academia interactions through novel program
of knowledge partnerships in genomics and
bioinformatics.
·
Knowledge Alliance
Dr.
Brahmachari has positioned IGIB as Institution of
Knowledge generation and Development and established
alliances with industries who are expert in
production, marketing and wealth generation. GENOMED
Alliance and TCGA project are outcomes of such
strategy.
Dr.
Brahmachari was first to conceptualize and implement
Genomed,
a
first-of-its-kind alliance in India between a
government Institute and a pharmaceutical company -
Nicholas Piramal India Limited & a CSIR lab - Centre
for Biochemical Technology (CBT) now IGIB. This
knowledge alliance was dedicated to the study and
advancement of genomics, pharmacogenomics and
bioinformatics. This model allowed knowledge
generation and absorption by industry simultaneously
and this was distinctly different from contractual
research or technology transfer. The first
predictive diagnostic medicine for drug
nonresponders of Asthma has been developed. The
project has so far filed 2 international patents.
Dr.
Brahmachari has also conceptualized creation of
TCGA, “The Centre for Genomic Application”.
It is a collaborative R&D project between The
Chatterjee Group and IGIB/CSIR/DST that is used as a
shared resource for all the research centers in the
country, be it public or private. TCGA is a
trendsetter in this direction, where a world class
high throughput facility / infrastructure required
to harness the knowledge coming out Human Genome
research is established jointly by industry and the
Institute. This facility is allowing IGIB to lead
Genomics research in the country by disseminating
its knowledge, help in fulfillment
of
IGIB’s mandate to provide support services for
large-scale development of Genomics & Proteomics in
the country allowing India to lead, and not to
merely follow, in the post genomics era. 77
institutions and 250 scientists have availed the
services of TCGA.
In
summary, Dr. Brahmachari has shown exemplary
scientific leadership and has made contribution in
the area of Functional Genomics with special
emphasis on molecular genetics of neurological and
psychiatric disorders and functional Genomics in
silico. Dr. Brahmachari’s scientific contribution
has positioned IGIB in the world genome research map
(Nature, Vol. 436; pp 480-483 and pp 492-495; 28th
July, 2005).
·
Teaching Experience
1)
Involved in courses in
Bio-molecular Structure; Biophysical Chemistry, DNA
Structure-Function and Expression for a large number
of Ph.D. students at Indian Institute of Science for
18 years.
2)
Delivered over 200
lectures at various institutions, universities and
colleges in the country on Human Genome Project and
Genome Analysis Technology.
3)
Has delivered lectures for the
Integrated Ph.D students of
B. R.
Ambedkar Centre for Biomedical Research, University
of Delhi, Delhi from 1998 onwards.
·
Dr. Brahmachari’s contribution in
Institutional Transformation
Relatively unknown Centre for
Biochemical Technology of CSIR underwent major
transformation over the last 10 years to emerge as a
leading institute of Genomics & Integrative Biology
in the country. The scientific production and
quality grew from 7 publication (Avg. IF 1.01) in
1996 to 75 (Avg. IF 3.30) in 2006 and expected to
reach higher in 2007. It also acquired an impressive
portfolio of 67 foreign and national patents (and
176 pending patents). IGIB’s patent portfolio has
caused value realization and IP asset creations and
has attracted foreign and national collaborations
and project funding. The following are the salient
achievements of CBT/IGIB during the last 10 years.
1998- IGIB established
largest clinical network in India
2000- First Knowledge
Alliance ‘GenoMed’ with NPIL
2002- G.N. Ramachandran Knowledge Centre
for Genome Informatics established through private
funding to attract IT Professionals
2003- First Bioinformatics
Software of CSIR Commercialized
2004- Largest Private – Public partnership
TCGA “The Centre for Genomic Application”
(co-shared facility) established
2005- First Genomic marker
for drug response discovered
2005- Largest High
Performance Computing facility (4.7 tera flops)
established
2005- India’s highest number
of co-authored (158) paper published
2005- First Recombinant Growth Factor drug
REGEN-D launched (Technology Award 2006)
2005- HP Centre of
Excellence in Bioinformatics in Asia.
2005- IGIB among the World’s best
Bioinformatics Institutes for developing PML 2
protocol
2006- First Bioincubator
“Eclosion” being established
2005-2006- IGIB attains highest
number of paper, total IF, Patents and ECF per
scientist
2007- IGIB coordinated Indian Genome
Variation project provided the Genetic landscape of
people of India: A canvas for affordable predictive
medicine development and for informed policy level
decision for Adverse Drug Reaction and disease (like
HIV, Malaria, Diabetes, CVD etc.) management
2007- Initiated a novel programme on Open
Source Drug Discovery platform for infectious
diseases
2007- Launched a programme on
pharmacogenomics to keep affordable drugs in the
market.
Visits Abroad
·
1979-1996
1.
Participated in workshop on “Chromatin structure”. Weizmann
Institute of Sciences. Rehovot, Israel, March 1979.
2.
Visiting Scientist to
Dept. of Biochemistry, Memorial University of
Newfoundland, St. Johns Newfoundland, Canada, Nov.
1979.
3.
Participated in first
AMBO meeting on “Future of Nucleic Acid Research” in
Kyoto, Japan, Dec, 1981, and visited several
laboratories in Japan during 26th Nov. to
22nd Dec, 1981.
4.
Visitor, University of
Ulm, West Germany, May 1985.
5.
Participation and paper
presentation at the IVth conversation in
Biomolecular Stereodynamics, Albany, N.Y.USA, June
1985.
6.
Visiting Scientist,
Dept. of Human Genetics and Development, University
of Columbia, N.Y. USA, June-Sept. 1985.
7.
INDO-USSR ILTP exchange visit.
Institute of Molecular Biology, USSR
Academy of Sciences, Moscow, May 1988.
8.
Symposium speaker, 6th
Convention in Biomolecular Stereodynamics, Albany,
N.Y., USA, June 1989.
9.
Visitor, Dept. of
Biochemistry, Oxford University, Oxford, UK, June
1989.
10.
Visitor, Dept. of
Biochemistry, Tufts University, Boston, USA. June
1989.
11.
Invited, speaker, 2nd
International symposium of Protein Structure
Functions, University of Karachi, Pakistan, Dec
1989.
12.
Participated and
presented poster at the Gordon Research Conference
on “Nuclear Proteins, Chromatin Structure and Gene
Regulation” Tilton school, New Hampshire, USA, July
1990.
13.
Visitor, Dept. of
Biology, Massachusetts Institute of Technology,
Cambridge, USA, July 1990.
14.
Participated and
presented paper at 10th International
Biophysics Congress of IUPAB Vancouver, Canada, 29th
July-3rd August 1990.
15.
Visiting Scientist,
Dept. of Molecular Biology, Stanford Research
International, Stanford, California, USA, Aug 1990.
16.
Invited speaker,
International Symposium on “Synthetic
Oligonucleotides: Problems and Frontiers of
Practical Application”, Shemyakin Institute, Moscow,
June 1991.
17.
INDO-USSR ILTP exchange visit.
Institute of Molecular Biology, USSR
Academy of Sciences, Moscow, July 1991.
18.
Symposium speaker, 8th
Conversation in Biomolecular Stereodynamics, Albany,
N.Y., USA, June 1993.
19.
Visitor, Dept. of
Biophysics, University Paris Nord, Paris, France,
June 1993 (Hosted by Prof. E. Taillandier).
20.
Visitor, Dept of
Biophysics, Museum National D’Histoire Naturelle,
Paris, France, 1993 (Hosted by Prof. C. Helene).
21.
Visitor, Dept. of
Chemistry, New York University, New York University,
New York, USA, 1993 (Hosted by Prof. N. R.
Kallenbach).
22.
Visitor, NIDDKD,
National Institute of Health, Maryland, USA, 1993
(Hosted by Prof. H. T. Miles).
23.
Visitor, Dept. of
Molecular Biology, National Institute of Health,
Maryland, USA, 1993 (Hosted by Dr. S. Adhya).
24.
Visitor, Dept. of
Chemistry, University of Rutgers, New Jersey, USA,
1993 (Hosted by Prof. Wilma Olson).
25.
Visitor, Dept. of
Biology, MIT, Cambridge, Boston, USA, 1993 (Hosted
by Prof. A. Rich).
26.
Visitor, Dept. of Human
Genome Centre, Boston University, Cambridge, USA,
1993 (Hosted by Prof. Charles R. Cantor).
27.
Visitor, NIG, Japan,
1996 (Hosted by Prof. T. Gojobori).
28.
Visitor, Genome Science
Laboratory, Riken, Japan 1996 (Hosted by Dr. Y.
Hyashizaki).
29.
Visitor, Banyu Tsukuba
Research Institute, Tsukuba, Japan, 1996 (Hosted by
Prof. Susumu Nishimura).
30.
Visitor, Human Genome
Centre, Tokyo, Japan, 1996 (Hosted by Prof.
Yoshiyuki Sakaki).
31.
Invited Speaker, Human
Genome Treaty Symposium, Berlin, Germany, October
1996.
32.
Visitor, Institute of
Human Genetic, Berlin, Germany, October, 1996
(Hosted by Prof. Karl Sperling).
33.
Visitor, Institute fur
Kristallagraphie, Germany, October 1996 (Hosted by
Prof. W. Saenger).
34.
Visitor, Max-Planck
Inst. fur Biophysical Chem, Germany, October 1996
(Hosted by Prof. T. M. Jovin).
35.
Visitor, Max-Delbruck
Centre for Molecular Medicine, Berlin, Germany
October 1996 (Hosted by Dr. U. Heinmann).
36.
Visitor, Genetique
Medicale Et. Development, Marseille, France, October
1996 (Hosted by Prof. M.Fontes).
·
1997 onwards
1.
Senior visiting
scientist, Max-Planck Inst. for Biophysical Chem.
Goettingen, Germany, May-June 1997.
2.
Attended the council
meeting of the FAOBMB & the 8th FAOBMB
Congress, Kuala Lumpur, Malaysia, November 1998.
3.
Attended and delivered
invited talk at the Indo-Israel Golden Jubilee
Conference, Israel, December 1998-January 1999.
4.
Attended the Council
meeting of the FAOBMB, Delivered invited symposium
lecture at 14th FAOBMB Symposium,
University of Otago, Dunedin, New Zealand, November
1999.
5.
Delivered invited
lecture at Institute for Biomedical Research,
University of Sydney, Sydney, December 1999.
6.
Attended the
International Colloquium entitled “Life Sciences,
Ethics, Economy & Society” at University of
Bordeaux-I, France, June 2000.
7.
Attended 2nd
Indo –US Round Table Dialogue meeting in Washington
DC, September 2000.
8.
Invited speaker at an
International Symposium on “Ethics, Intellectual
Property and Genomics” at UNESCO Headquarters,
Paris, 30th January-1st
February 2001.
9.
Attended and delivered
invited talk at the Working Group Meeting as a
follow up of the symposium on “Ethics, Intellectual
Property and Genomics” at UNESCO Headquarters,
Paris, 13th –14th June 2001.
10.
Attended and delivered
invited talk at the Symposium on Bioethics in
Austria 21st-23rd November
2001.
11.
Attended and delivered
invited talk at the Conference on Expert Group on
Human Rights and Biotechnology at Geneva 23rd
– 25th January 2002.
12.
Invited Speaker for HGM
2002 workshop at Shanghai 14th – 17th
April 2002.
13.
Attended and delivered
invited talk at the conference on “Bioscience Asia
2002” at Taiwan 20th – 23 rd
May 2002.
14.
Attended Indo-South
African Workshop on advanced computing, organised by
Department of Science & Technology at Pretoria, S.
Africa, 28-29 October 2002.
15.
Invited speaker during
India Celebrations Day at Royal Society London, 11th
Dec 2002
16.
Participated in a
Workshop organised by the University of Mauritius to
help them in developing Bioinformatics and its
application to Academics and graduate students and
also to discuss and identify together with Academics
niche research areas in the Bio-informatics field,
18th to 25th October 2003.
17.
Participated in the 1st
Meeting of India-EC Steering Committee at Brussels,
Belgium from March 3rd to 5th,
2004.
18.
Visited Japan at the
invitation of Japan External Trade Organization
(JETRO)’s Support Programme for Japan- India
Business Matching in the Field of Biotechnology from
March 21st to 27th, 2004 at
delivered invited talk at JETRO.
19.
Visited Russia as a
member of the Indian delegation to Russia to
participate in the 12th Session of ILTP
Joint Council Meeting in St. Petersburg and Joint
Committee Meeting of the Russian-Indian Centre for
Ayurvedic Research in Moscow from September 30th
to October 4th, 2004.
20.
Visited Swiss Federal
Institute of Technology (EPFL), Lausanne,
Switzerland to develop collaborative project under
the Indo-Swiss Collaboration Programme to identify
promising areas in Life Sciences and for business
development during October 5th to 7th,
2004.
21.
Participated at the
HUGO Council meeting at Toronto, Canada on 27th
October, 2004.
22.
Headed the Indian
delegation participating in the Sino-Indian Workshop
on Genome Informatics held at Hangzhou, China from
October 27th to November 2nd, 2004.
23.
Invited speaker at the
HUGO Pacific Meeting in Singapore November 17-20,
2004 and took part in the Pan Asian SNP Consortium
meeting in Singapore on 18th November, 2004.
24.
Invited speaker,
Council Member and the Chairman of the Fellowship
Committee at the FAOBMB/IUBMB/A-IMBN Meeting held at
Bangkok, Thailand from 22nd to 26th November, 2004.
25.
Invited speaker at the
International Conference Asia Biotech Forum 2005 at
Kuala Lumpur from 3rd to 4th
February, 2005.
26.
Invited speaker at the
Workshop entitled “Health of Populations in the
Mediterranean in the post genomic era” in Tunisia
from 4th to 5th March, 2005.
27.
Attend the India Pharma
Fund Limited inaugural board meeting at Mauritius on
17th March, 2005.
28.
Delivered an invited
talk at the HUGO’s Tenth International Human Genome
Meeting, HGM2005, Kyoto, Japan, from 18th
to 21st April, 2005 and took part in the
Pan Asian SNP Initiative Executive Committee Meeting
and the Pan-Asia SNP Initiative Policy Review Board
(PRB) Meeting.
29.
Attended and delivered
invited talk at the Workshop on “Promoting and
Facilitating Innovation driven new ventures”, held
fro 29th May to 3rd June, 2005
at Technion – Israel Institute of Technology, Haifa,
Israel.
30.
Invited talk at the
Albany 2005: The 14th Conversation at
Albany, NY, USA from 14th -18th
June, 2005.
31.
Invited talk at the
Annual Convention of BIO 2005 in Philadelphia, USA
from 19th-21st June 2005 and .was a speaker at the
CII Session on " India in the wake of 2005: A Hub of
Innovation."
32.
Visited Centre National
de la Recherche Scientifique (CNRS), Paris, France
from 23rd -25th June 2005 to
discuss about possible future collaborations and
prepare for joint projects in the area of Integrated
Systems Biology for Health.
33.
Attended the India
Pharma Fund Limited board meeting at Mauritius on 4th-5th
July 2005.
34.
Attended and delivered
invited talk at the 2005 International Symposium on
Computational Biology & Bioinformatics (ISCBB2005)
in Tokyo, Japan on 28th October, 2005.
35.
Delivered invited talk
at the meeting on Integrative Systems Biology for
Health -TRANSCRIPTOME 2005 at Shanghai, China from 5th
-10th November, 2005.
36.
Attended the India
Pharma Fund Limited board meeting at Mauritius on 10th-11th
January, 2006.
37.
Delivered invited talk
the Taiwan-India Joint Symposium on Functional
Genomics at Taipei, Taiwan on 3rd-4th
March, 2006.
38.
Invited lecture at the
HUGO Asia Pacific Meeting held at Taipei, Taiwan
from 6th-10th March, 2006.
39.
Visit and invited talk
at the Dept of Bioorganic Chemistry, Uppsala
Universitet, Uppsala, Sweden, May 2006 (Hosted by
Prof. Jyoti Chattopadhyaya).
40.
Invited as a Chairman
at the Bioinformatics Workshop at HUGO’s Eleventh
International Human Genome Meeting, HGM2006 at
Helsinki, Finland from 31st May to 3rd June, 2006
and also delivered invited lecture in the EU
Workshop on 3rd June, 2006.
41.
Attended the India
Pharma Fund Limited board meeting at Mauritius on
14th June, 2006.
42.
Invited talk at the
Human Variome Project Meeting at Melbourne,
Australia from 20th to 23rd June, 2006.
43.
Invited talk at the
2006 International Conference on Genomics in
Hangzhou, China from 23rd – 25th
October, 2006.
44.
Attended the Data
Analysis and Manuscript Writing Meeting of the Pan
Asian SNP Initiative in Singapore from 9th
– 11th November, 2006.
45.
Attended the 3rd
Meeting of the India-EC Steering Committee on S&T
Cooperation at Brussels, Belgium on 16th
& 17th November, 2006.
46.
Invited to the 2nd
UKIERI (UK-India
Education and Research Initiative)
Evaluation Panel meeting at London, UK on 28th
– 29th November, 2006.
47.
Visit to the University
of Leicester, UK at the invitation of Prof. Anthony
Brookes on 1st December, 2006.
48.
Attended the India
Pharma Fund Limited board meeting at Mauritius on
16th January, 2007.
49.
Attended the Manuscript
Writing Meeting of the Pan Asian SNP Initiative in
Singapore from 20th – 21st
March, 2007.
50.
Invited as a Chairman
at the Bioinformatics Workshop at HUGO’s 12th
International Human Genome Meeting, HGM2007 at
Montreal, Canada from 21st to 24th
May, 2007.
51.
Visit in USA to
Research Triangle Institute International, NC;
National Human Genome Research Institute, Bethesda;
invited talk at the National Cancer Institute, NIH,
Bethesda and Center for Complex Disease, Genomics
McKusick - Nathans Institute of Genetic Medicine,
Johns Hopkins University, Baltimore from 25th
May to 3rd June, 2007.
TOP ^
Invited Lectures delivered at various
International laboratories, National and
International Conferences
·
Lectures delivered in National Forum
1.
Invited speaker, INDO/FRG
seminar, Molecular Biology and Agriculture division,
BARC Bombay, India, March 1982.
2.
Invited speaker, Int.
Symposium on Genome organisation and Expression in
development, Differentiation and Neoplasia, Dept. of
Zoology, University of Poona, Pune, Feb. 1984.
3.
Invited speaker, Int.
Symposium On Biomolecular structure and
interactions, IISc. Bangalore, Dec. 1984.
4.
Invited Speaker, XII
Annual meeting of Indian Biophysical society, Dept.
of Biochemistry, University of Mysore, Mysore, Feb.
1985.
5.
Invited Speaker, 54th
Annual meeting of the Society of Biological
Chemists, Panthnagar, India, Nov. 1985.
6.
Invited speaker, Int.
Symposium on Immunochemistry, Structure and Function
of Nucleic Acids, IISc., Bangalore, July 1987
7.
Invited speaker,
Mahabaleshwar Seminar in Modern Biology on
“Molecular Evolution”, Oct. 1987.
8.
Invited speaker,
Symposium of Genetic Engineering Research in India,
IISc. Bangalore, July 1988.
9.
Invited speaker,
INDO-SOVIET symposium on Genetic Engineering, IICB,
Calcutta, March 1989.
10.
Invited speaker,
International symposium on Bioseparation, CSIR
Centre for Biochemicals, New Delhi, December 1989.
11.
Guha Research
Conference, Lakshadweep, India, 9th-13th
January 1990.
12.
Symposium speaker,
INDO-SOVIET workshop on “DNA-Protein interaction and
cross-linking” Bangalore, India. 21st-25th
March 1990.
13.
Invited Speaker,
National Symposium on Biophysics, Madras, February
1991.
14.
Guha Research
Conference, Udaipur, India, March 1991.
15.
Invited speaker, 57th
Annual Meeting of the Academy, Pune, November 1991.
16.
Invited speaker, “Gene
Structure and Expression” symposium, IISc,
Bangalore, December 1991.
17.
Guha Research
Conference, Kemmangundi, India, December 1991.
18.
Invited speaker,
Diamond Jubilee Annual General Body Meeting, Society
of Biological Chemistry, Calcutta, December 1991.
19.
Invited speaker,
“Regulation of Gene Expression” Nagarbhavi,
Bangalore, January 1992.
20.
Dept. of Anatomy, All
India Institute of Medical Sciences, New Delhi,
India, Feb 24th-6th March
1992.
21.
Dept. of Biotechnology
(India), Extension Lecture, Dept. of Biochemistry,
Gulbarga University, Gulbarga, India, July 1992.
22.
Symposium speaker,
Trends in DNA Structure-Function and Genome
Organization, 11th-14th Jan,
Bangalore, 1993.
23.
Invited speaker,
“Biophysics Symposium”, Calcutta, February 1993.
24.
Guha Research
Conference, Dalhousie, India, May 1993.
25.
Invited speaker,
“International Symposium on Cellular & Molecular
Aspects of Developmental Regulation” Pune, November
1993.
26.
Invited speaker, “INSA
Golden Jubilee Symposium” Delhi, January 1994.
27.
Invited speaker,
“Symposium on Bioinformatics: The current scenario”,
Calcutta, 1994.
28.
Invited speaker, “Gene
Therapy”, Delhi, September 1994.
29.
Symposium speaker, 16th
International Congress of Biochemistry and Molecular
Biology, Delhi, September 1994.
30.
Symposium speaker,
Asian Conference on Transcription (ACT III),
Bangalore, September 1994.
31.
Invited speaker,
“Emerging Areas in Science and Technology”, Jorhat,
October 1995.
32.
Symposium speaker,
“Third International Symposium on Genetics, Health
and Disease”. Amritsar, December 1995.
33.
Symposium speaker,
“South-North Human Genome Conference”, Delhi
December 1995.
34.
Symposium speaker,”
Genome Analysis: Recent Trends and Applications”,
Hyderabad, January 1996.
35.
Invited speaker,
“Genome 96: Workshop on Biotechnology”, Bangalore,
January 1996.
36.
Invited speaker,
“Transcription Assembly”, Hyderabad, August 1996.
37.
Invited speaker,
Society of Biological Chemists, Bangalore, Sept.
1996.
38.
Symposium speaker, “MBU
Silver Jubilee Symposium on Structural Biology”,
Bangalore, Dec. 1996.
39.
Guha Research
Conference, Mirik, India, December 1996.
40.
AP Mitra Memorial
Lecture, Dept. of Chemistry, Delhi Univ., Delhi,
September, 1997
41.
Diversity in Modern
Biology – An Interdisciplinary Symposium, University
of Delhi, South Campus, N. Delhi, September, 1997.
42.
International Hands-on
Training Course on DNA Fingerprinting, CCMB
Hyderabad, India, November, 1997.
43.
46th Annual
Conference of Neurological society of India, Jaipur,
India, December 1997.
44.
Dept. of Anthropology,
Univ. of Delhi, Delhi, December 1997.
45.
49th Indian
Pharmaceutical Congress, Thiruvanthapuram, India,
December 1997.
46.
Anniversary meeting of
INSA, Hyderabad Univ., Hyderabad, India, December
1997.
47.
Winter school on Human
Genetics, I.S.I., Calcutta, January, 1998.
48.
Second annual National
Convention of ADNAT, CCMB Hyderabad, March 1998.
49.
National Defence
College, New Delhi, March 1998.
50.
Jawahar Lal Nehru
University, New Delhi, March 1998.
51.
Vision for
Neurosciences in next millennium, Indian Habitat
Centre, New Delhi, March 1998.
52.
Seminar on Science &
Technology-21st century challenges
(ST-2000), Jamia Millia Islamia, New Delhi, March
1998.
53.
Indo-French Workshop on
new Opportunities in Molecular Technologies, Ashoka
Hotel, Bangalore, March 1998.
54.
Frontiers in Biomedical
Research, Ambedkar Centre for Biomedical Research,
University of Delhi, Delhi, April 1998.
55.
All India Institute of
Medical Sciences, New Delhi, April 1998.
56.
Director’s Conference,
NAL, Bangalore, May 1998.
57.
National Academy of
Sciences, Allahabad 1998.
58.
St. Stephen’s College,
Delhi, September 1998.
59.
Delhi University,
Botanical Society, Dept. of Botany, Delhi
University, Delhi.
60.
5th Annual
Symposium Ranbaxy Science Foundation, Gurgaon, NII,
New Delhi, October, 1998.
61.
International Update on
Neurosciences, All India Institute of Medical
Sciences, New Delhi, November 1998.
62.
Workshop on Sequence
Analysis & Molecular Modelling, School of Life
Sciences, Jawahar Lal Nehru University, New
Delhi, December 1998.
63.
67th Annual
Meeting of Society of Biological Chemists (I),
School of Life Sciences, Jawahar Lal Nehru
University, New Delhi, December, 1998.
64.
86th
Session of the Indian Science Congress Association,
Anna University, Chennai, January 1999.
65.
Workshop on “DNA Isolation from Forensic Specimen &
STRs analysis”, Central Forensic Science Laboratory,
Calcutta, March 14-26, 1999.
66.
Golden Jubilee Celebrations, VP Chest Inst. Delhi,
April 1999.
67.
Symposium on Research in Molecular Biology and
Biotechnology in India: Challenges in the next
millennium, India Institute of Chemical Biology,
Calcutta, September 1999.
68.
National Symposium on Bimolecular
Electronics-Interfacing Physics and Chemistry with
Biology, National Physics Laboratory, New Delhi,
September 1999.
69.
Sixty
fifth Annual meeting, Indian Academy of Sciences,
CDRI, Lucknow, October 29-31, 1999.
70.
Trends in Biochemistry, Sixth meeting, Department of
Biotechnology, University of Delhi, New Delhi,
November 23-24, 1999.
71.
Invited lecture at
Miranda House College, Delhi, December 1999.
72.
68th Annual
Meeting of SBC (I) & Symposium on Current Trends in
Biology, Indian Institute of Science, Bangalore,
December 27-29, 1999.
73.
Millennium Lecture at
87th Science Congress in Plenary Session
Emerging Frontiers in Basic Science and Technology,
Pune, Jan 4th 2000.
74.
Symposium on Impact of
Science on Society in next Millennium at Vivekananda
Institute of Medical Sciences, Calcutta, 7th
Jan 2000.
75.
Invited lecture at
National Aerospace Laboratories Bangalore, July 20th,
2000.
76.
Seminar on Beyond
Genome- Bioinformatics and Drug Research, CII,
Delhi, July 25th 2000.
77.
Seminar on Developing
India’s Capability In Genomics: New Era of Public –
Private Partnership in Genomics IT & Medicine,
FICCI, New Delhi, July 26th 2000.
78.
Seminar on Beyond
Genome- Relevance for India, CII, Delhi, July 25th
2000.
79.
Colloquium on The Human
Genome: Scientific and Ethical Implications, Centre
for Philosophy and Foundations of Science, New
Delhi, August 7th, 2000.
80.
Invited lecture at the
Training Programme for Senior IAS Officers, Lal
Bahadur Shastri National Academy of Administration,
Mussoorie, 17th August 2000.
81.
Invited lecture at
Defence Science Forum, Metcalfe House, Delhi, August
24th 2000.
82.
Invited lecture at
Kirori Mal College, Delhi, 27th September
2000.
83.
INDO-CUBA Workshop on
Biotechnology in health care, INMAS, Delhi, 3rd
October 2000.
84.
Seminar on India Chem
2000 Conference, FICCI, New Delhi, 6th
October 2000.
85.
Invited lecture during
the Biotechnology Conference organised by Chemtech
Foundation, Mumbai, 10th November 2000.
86.
Invited lecture on 5th
International meeting on “Molecular Epidemiology and
Evolutionary Genetics of Infectious diseases”, CDFD,
Hyderabad, 14th November 2000
87.
Invited lecture at
Daulat Ram College, Delhi, 16th November
2000.
88.
Invited lecture at
National Science Centre during the symposium
Biotechnology India 2000 organised by Exhibitions
India Pvt. Ltd, 29 November 2000.
89.
Invited lecture at
International Workshop on “Innovation in Science and
Technology: Economic, philosophical and social
dimensions” held at CSIR Science Centre, organized
by NISTADS, 5th December 2000.
90.
Delivered lecture at
Indian Institute of Chemical Biology, Calcutta
during the 69th Annual meeting of the
Society of Biological Chemists (India), 8th
December 2000.
91.
Invited lecture at
Chembiotech, Calcutta during the symposium Chemcon
2000, 19th December 2000.
92.
Seminar on
“Haemoglobinopathies-South Asia-Problems and
Prevention” at Vivekananda Institute of Medical
Sciences, Calcutta, 29th December 2000.
93.
Invited lecture at J.
N. Tata Auditorium, National Science Seminar
Complex, IIS Campus Bangalore organised
Confederation of Indian Industry, India, 16th
January 2001.
94.
Invited lecture on
“Information Technology & Biotechnology: Bridge over
Genome River at M. S. Ramaiah School of Advanced
Studies, Bangalore 17th January 2001.
95.
Delivered a lecture at
Chemistry Society Hindu College, Delhi University,
24th January 2001
96.
Delivered a lecture on
“DNA Microarray Technology” Workshop at IISc
Bangalore, 19th February 2001.
97.
Delivered a lecture in
the “ISHG-2001” XXVI Annual Conference of the Indian
Society of Human Genetics at CCMB Hyderabad, 21st
February 2001.
98.
Delivered a lecture in
the Workshop cum Seminar on Bioinformatics during
the national symposium – Biohorizon 2001 at IIT,
Delhi, 24th February 2001.
99.
Delivered a lecture
during the national Conference on “Human Genome-The
Prospective Research Strategies” at Post Graduate
Institute of Medical Education & Research,
Chandigarh, 24th-25th August
2001.
100.
Delivered a lecture at
the meeting on “Biomolecular Conformation and
Function” at Indian Institute of Science, Bangalore,
26th July 2001.
101.
Delivered a lecture on
“The Human Genome Research and its Social
Implications” at Indian Agricultural Research
Institute, New Delhi, 29th August 2001.
102.
Round Table Discussion
on Genomics, IISc Bangalore, 3rd
September 2001.
103.
“Population
Polymorphism Scanning: A functional genomics
approach”, for the society young Scientist at AIIMS
at 7th September 2001.
104.
INDO GERMAN Symposium
on Genomics at Chandigarh 18th September
2001.
105.
Delivered three Lectures at IIT,
Kanpur: “Functional Genomics in silico”,
“Population Polymorphism Scanning: A Novel method
for Gene Function Discovery” and “Public Lecture:
Beyond the Human Genome Sequence”. 15th –
16th October 2001.
106.
Delivered a Talk at MV
Symposium, IISc Bangalore, on PLHOSTFA
novel tool for identification of Functional
signatures and Comparative genomics 22nd
– 29th November 2001.
107.
“DNA Microarray
opportunities and Challenges ahead”, at
Mini-symposium ICGEB, New Delhi. 30th
November 2001.
108.
Delivered a Lecture at
Workshop on Functional Genomics at ISI, Kolkata. 11th
December 2001.
109.
Delivered a talk on
“Genomics and New Drug Discovery” at Goa. 15th
December 2001.
110.
Delivered a talk
“BT-IT: Bridge over River Genome” at Techfest, IIT-
Mumbai.2nd February 2002.
111.
Delivered a talk on
“BT-IT: Bridge over River Genome” at IIT, Kharagpur.
11th February 2002.
112.
Delivered a Lecture
“PLHOSTFA novel tool for identification
of Functional signatures and Comparative genomics at
ADNAT Symposium CCMB, Hyderabad. 23rd
February 2002.
113.
Delivered a talk on
“Population Polymorphism Scanning: A Functional
Genomics approach at INDO French workshop INSA on 4th
March 2002.
114.
Delivered lecture
during the Pharmacogenomics meeting at DBT on July
11th
2002.
115.
Delivered an invited
lecture at Regional Research Laboratory, Trivandrum
on Beyond the Human Genome Sequence: Predictive and
Personalised Medicine” on November 22th
2002.
116.
Delivered lecture at
CCMB, Hyderabad on “Comparative and Functional
Genomics In silico” in the International Knowledge
Millennium Conference at the Symposium `The Current
Excitement in Biology’ on November 24-29th
2002.
117.
Delivered a talk on “Comparative and
Functional Genomics: New opportunities and
Challenges” at Bundelkhand University, Jhansi during
the `Emerging Areas in Biomedical Sciences’ on
December 28-30th,
2002.
118.
Delivered invited
lecture in the celebration of `50 years of DNA
Double Helix’ at Guru Gobind Singh Indraprastha
University on the topic “From Helix to Genomics – A
50 year Saga” on January 11th,
2003.
119.
Delivered lecture
during the Workshop `Knowledge Discovery in Genomics
& Proteomics Bio informatics Approach’ at Pune
University on January 15th,
2003.
120.
Delivered lecture on `The Need for
Grand Vision and Microplanning’ at CIMAP Lucknow
during the Annual Meeting of Planning and Business
Development Scientists on January 22-23th,
2003.
121.
Delivered lecture Title: “B.K.
Bachhawat Memorial Lecture” during the Symposium
`Frontiers in Molecular Medicine’ at Jawahar Lal
Nehru University on February 10th,
2003.
122.
Delivered lecture
Title: “Comparative Genomics: An Approach to
Seamless Biology” during the Yeast 2003 Symposium at
IMT in March 2003.
123.
Delivered lecture on
"Human Genome Project" at the Shaheed Rajguru
College of Applied Sciences for Women, Univ. of
Delhi on February 26th,
2003
124.
Delivered lecture on
`Beyond the Human Genome Sequence: Predictive and
Personalized Medicine’ in DIPAS, Delhi on February
28th,
2003.
125.
Delivered lecture on
23.3.03 during the Knowledge Millennium III- the
Business of Biotechnology organised by ASSOCHAM
during March 21-23th,
2003.
126.
Delivered lecture on
“Showcasing Institutional R&D: IGIB” in Bangalore
Bio 2003 on April, 2003.
127.
Delivered Dr. C. R.
Krishnamurthy Award lecture at CDRI, Lucknow on
March 4th,
2003
128.
Delivered lecture in a
symposium on “Genomics: Challenges and
opportunities, at Hyderabad on April, 2003
129.
Delivered lecture
during workshop on "Genetic Epidemiological Methods
for dissection of complex human traits" at ISI,
Kolkata on 11 June 2003.
130.
Delivered lecture at
Miranda House, Delhi University on "Borderless
Science: Integration of Biology, Chemistry and
Information Technology", on Sep 22nd
2003.
131.
Delivered lecture on
Role of Bioinformatics in Genomics" in Symposium
"Computational challenges in Bioinformatics" at C-DAC,
Pune on 5th Nov 2004.
132.
Delivered lecture on "SNPs,
Chips, Informatics and Predictive Medicine" at ITRC,
Lucknow on 7th Nov 2003.
133.
Delivered Talk on "IPR
& PPP In Biotechnology" on 17th Nov 2003
at TERI Retreat, Delhi.
134.
Delivered lecture at
Sri Venkateswara College, Delhi University on
"Borderless Science: Integration of Biology,
Chemistry and Information Technology", on Nov 26th
2003.
135.
Delivered lecture at
FAOBMB Symposium at IGIB, on "Variation and
Conservation: a balancing act in genome" on 6th
Dec 2003.
136.
Delivered lecture on
"Functional Genomics to System Biology: Integration
of Information Technology to biology" at Indian
Science Congress, 3-7 Jan 2004, Chandigarh.
137.
Delivered lecture on
"Functional Genomics to System Biology: Integration
of Information Technology to biology" at All India
Cell Biology Conference & International Symposium,
Pune on Jan 9th 2004.
138.
Delivered talk on
"Globalization of Biotech R&D: Role of Indian
Institutions" in CII conference "BioEconomy-Growth
Engine of 21st century" on 5th Feb 2004.
139.
Delivered talk on "New
Horizons in BioTechnology - Planning for the
Century" at TIFAC, Delhi on 10th Feb
2004.
140.
Delivered talk on
"Challenge of Managing Creativity" at TERI Retreat,
Delhi on 11th Feb 2004.
141.
Delivered talk on
“Three Decades @MBU: Triple Helix to Genomics” at
Molecular Biophysics Unit, Indian Institute of
Science, Bangalore on 29th April, 2004
142.
Delivered inaugural and
keynote lecture at Indo-Tunisian Workshop on
Bioinformatics in Medicine on 28th June,
2004 at Delhi on “Predictive Medicine in Genomic
Era”.
143.
Delivered a lecture on
“Beyond the Human Genome Sequence” at Kulachi
Hansraj Model School, Delhi on 28th June
2004.
144.
Delivered 14th
G.S.Sidhu Science Lecture at IICT, Hyderabad on 2nd
July 2004 on “SNPs, Chips, Informatics and
Predictive Medicine”.
145.
Talk on “Public –
Private Partnership in Biotech R&D” at IIM,
Ahmedabad on July 3rd, 2004.
146.
Invited lecture at 4th
Management Development Programme on harnessing
Intellectual Property for Strategic Competitive
Advantage on July 3rd 2004 at IIM,
Ahmedabad on “IP Mediated technology collaboration
between public and private sector”.
147.
Delivered talk at
Bangalore Bio 2004 on 12th July 2004 in
the session ‘Current Advances in Biotechnological
Session’ on “Functional Genomics to System Biology-
Integration of Information Technology to Biology”.
148.
Delivered plenary talk
“Predictive Medicine in Genomic Era” at
Indo-Tunisian Workshop on Bioinformatics in
Medicine, New Delhi on 28 June 2004.
149.
Delivered invited
lecture on “SNPS, Chips, Informatics and Predictive
Medicine” at “Genomics 2004: Challenges and
opportunities” organised by National Centre for
Plant Genome Research, Delhi on 13th
September, 2004.
150.
Delivered talk on
“Science and Business of Bioinformatics: Will India
Lead or Follow?” at Centre for DNA Fingerprinting
and Diagnostics, Hyderabad on 14th
September 2004.
151.
Delivered lecture as
faculty of the INSA sponsored workshop on Genomics and Medicine at
University College of Medical Sciences, Delhi on 23rd
September, 2004.
152.
Delivered talk on
“Public – Private Partnership in Biotech R&D
Opportunities in Life Sciences” at Technology Summit
& Technology Platform 2004, organised by CII in
Delhi on 19th October, 2004.
153.
Delivered Invited
Lecture on “ “Dare to Dream & Dream to Dare”: Need
for sustained Commitment to Implement Dreams” at CII
Conference “Building Innovative Pharma in India” on
5th Nov 2004 in New Delhi at the Session
“Branding India-The Hub of Innovation”.
154.
Delivered an invited
talk at the session on IITians Empowering India:
Global Competitiveness: Bio-technology at the pan
IIT meet on the 24th December 2004, entitled “Global
Competitiveness in Biotechnology: Need for
Innovation” held at Delhi.
155.
Chaired the session
‘Indian Goal in Genomics’ and delivered a talk on 6th
January, 2005 at the 92nd Session of
Indian Science Congress held at Ahmedabad, entitled
“Genomics to System Biology: An Overview”.
156.
Delivered an invited
lecture at Indian Statistical Institute, Kolkata on
17th January, 2005 on “Genome Research:
Where do we stand?”
157.
Delivered an invited
talk at the International Conference ‘50 years of
discovery of triple “Triple Helix to Comparative
Proteomics” organised by University of Pune.
158.
Delivered an invited
lecture at the Ramanbhai Foundation 2nd
International Symposium at Ahmedabad titled
“Comparative Proteomics in silico for Drug Target
Identification” on 24th January, 2005.
159.
Delivered invited talk
at the International Conference, BioAsia 2005 in
Hyderabad at the Student Forum entitled “Global
Competitiveness in Biotechnology: Need for
Innovation” on 10th February, 2005.
160.
Delivered a talk at
International Symposium on “Genes, Evolution and
Complex Diseases” at NCBS, Bangalore on 19th
February, 2005 at the Session “Bioinformatics
approaches to the study of complex diseases”:
“Schizophrenia as a Case Study”.
161.
Delivered an invited
talk at the ADNAT Convention / Symposium on
Molecular Medicine and Health in Hyderabad on 20th
February 2005 entitled “Comparative Proteomics for
Drug Target Identification”.
162.
Invited as ten Chief
Guest at the Book Release Ceremony ‘Microorganisms:
Their Biotechnological Applications’ on May 9th,
2005 at AMITY Campus, Noida and delivered a talk
entitled “Predictive Medicine and Health Research in
the Post-Genomic Era”.
163.
Delivered an invited talk at the 11th Technology
Summit & Technology Platform organized by CII, New
Delhi on 21st September, entitled “Indian
Biotech at the Crossroads of Development”.
164.
Delivered an invited
talk at the Symposium “Drug Discovery to Clinical
Trials” at Mumbai entitled “Current status of
India's strengths capabilities in early stage
research” on 6th October, 2005.
165.
Delivered a plenary
lecture at the Conference Molecular Mechanism of
Diseases and Drug Action (MMDDA 2005) at Saha
Institute of Nuclear Physics, Kolkata on 16th
November, 2005 entitled “Novel Genomic approaches to
understand complex disorders & host pathogen
interaction”.
166.
Delivered an invited
talk entitled “The Security Dimensions in Biological
Research” at the NISDA Security Conference 2005
“Conceptualizing Security in the 21st Century" on 19th
November, 2005 at Pune.
167.
Delivered invited talk
at the session ‘Bio Technology: Translating R&D into
Commercial Opportunities’ at the INFOCOM 2005,
Kolkata entitled “Leveraging Indian IT for Global
Drug Development” on 8th December, 2005.
168.
Delivered an invited
talk at the Annual Festival of the Chemistry Society
of the St. Stephen’s College,
Delhi University titled “Comparative Genomics and
Pathway Modeling approaches towards Novel Drug
Target Identification’ on 22nd December,
2005.
169.
Delivered the Kapil
Sood Oration at the UP NEUROCON, organized by the
Fortis HospitalsHospitals
titled “Predictive Medicine- from Bench to Bedside”
on 26th February, 2006 at Noida.
170.
Delivered a talk titled
“Keeping up with the Expectation in Science!” at the
Symposium Frontiers of Molecular Biology in the New
Millennium at Jawaharlal Nehru University, New Delhi
on 12th April., 2006.
171.
Delivered the
inaugural, keynote address at the Consultative
Meeting on National Innovation Systems (NIS) of
India entitled “Innovation Systems for R&D in
Genomics” on 19th September, 2006 at New Delhi
organized by United Nations Asian and Pacific Centre
for Transfer of Technology, DSIR, CDC and NRDC.
172.
Delivered invited talk
at the International meeting on RNAi at ICGEB, New
Delhi 06 entitled “MicroRNA mediated regulatory
networks: an in-silico
approach”
on 27th October 20.
173.
Delivered a talk at the
Jagadis Bose National Science Talent Search (JBNSTS)
Science Camp entitled “Joy of Doing Science:
Learning vs. Creativity” on 21st November, 2006 at
Kolkata.
174.
Delivered an invited
lecture at the 2nd Global Conference and Exhibition
on “India R&D 2006- Mind to Market” organized
jointly by FICCI and DST entitled “Positioning For
The Future : Need For Innovation” on 5th
December, 2006 at New Delhi.
175.
Delivered an invited
lecture at the EMBO International Workshop on Human
Evolution and Disease at Hyderabad on 7th
December, 2007 entitled “Genotype to Phenotype for
Complex Disorders: An Integrative Biology Approach”.
176.
Delivered an invited
plenary lecture at the International Winter School
on Bioinformatics organized by University of
Hyderabad in Hyderabad entitled “Genome Informatics:
Opportunities and Challenges Ahead” on 8th
December, 2006.
177.
Delivered an invited
talk at session on ‘Beyond Human Genome’ during the
75th Meeting of the Society for
Biological Chemists (SBC), India titled “Harvesting
the Human Genome Sequence: Need for an Integrative
Approach” at New Delhi on 11th December,
2006.
178.
Delivered an invited
talk in the National Science Festival organized by
St. Stephens College, Delhi titled “Becoming of a
Scientist: Learning vs. Creativity” on 20th
December, 2006.
179.
Delivered an invited
talk at the International seminar on Innovation,
Creativity and Enterprise organized by University of
Mumbai, Institute of Chemical Technology titled
“Innovation lead Institutional Transformation: A
Case Study” on 24th December, 2006 at
Mumbai.
180.
Delivered the Endowment
Lecture [Professor P. K. Bose Memorial Lecture for
the year 2004] at the 43rd Annual Convention of
Chemists held in the Department of Chemistry, Dr.
Babasaheb Ambedkar Marathwada University, Aurangabad
on 25th December, 2006 entitled
“Chemistry to Genomics: A Challenging Journey”.
181.
Delivered the
valedictory lecture at the XXXII Annual Conference
of ISHG, and International Symposium on
'Deconstructing Human Diseases: The Genomic
Advantage' at Kolkata on 16th February,
2007 entitled “Human Genome Research: Road Ahead”.
182.
Delivered the National
Science Day Lecture organized by Indian National
Science Academy (INSA), New Delhi on 28th
February, 2007 titled “IT for New Biology : Future
Challenges“.
183.
Delivered an invited
talk at the International High Performance Computing
(HPC) Users Conference on Leadership Computing for
Science and Industry organized at Indian Institute
of Science, Bangalore titled “Human Genome Research:
Computational Challenges Ahead” on 2nd
March, 2007.
184.
Delivered an invited
talk at the National Symposium on Current Trends in
Zoological Research organized by Presidency College,
Kolkata titled “IT for New Biology : Future
Challenges” on 10th March, 2007.
185.
Delivered an invited
talk at the National Conference on Health Care
Biotechnology in Bangalore titled “Genome
Sequence to Molecular Medicine: The Pharma Business
vs. Affordable Health for All” on 21st
April, 2007.
186.
Delivered an invited
talk at the International Symposium on Chromosomes
to Genome organized by Centre for Cellular and
Molecular Biology (CCMB) on 4th July 2007
titled “Looking for Disease Genes: Whole Genome
Association Studies vs. Systems Biology Approach“.
187.
Delivered the Prof. G.
N. Ramachandran Oration lecture at the
Bioinformatics Centre, University of Pune on 1st
August, 2007 titled “Tale of Two Cities: Hope and
Reality“.
188.
Delivered an invited
talk at the Biotechnology Seminar organized by
Modern School, Vasant Vihar, New Delhi titled “IT
for New Biology: Future Challenges” on 1st
September, 2007.
189.
Delivered the
Foundation Day lecture of Birbal Sahni Institute of Palaeobotany,
Lucknow titled “Human Genome Research: Road Ahead”
on 10th September, 2007.
190.
Delivered an invited
lecture at the 5th Global Knowledge Millennium
Summit: B2B in Biotechnology & Nanotechnology”
organized by ASSOCHAM, Delhi titled “Open Source
Drug Discovery: a solution for Infectious Diseases”
on 19th September, 2007.
TOP ^
·
Lectures delivered in International Forum
1.
National Cancer
Research Institute, Tokyo, Japan, Dec.1981.
2.
Dept. of Biophysics and
Biochemistry, Faculty of Science, University of
Tokyo, Japan, December 1981 (Hosted by Prof. T.
Miyazawa).
3.
Dept. of Pharmacology,
University of Osaka, Japan, Dec. 1981 (Hosted by
Prof. M. Ikehara).
4.
Dept. of Physics,
Faculty of Science, University of Tokyo, Japan, Dec.
1981 (Hosted by Prof. A. Wada).
5.
Section Polymere,
University of Ulm, Ulm, West Germany, May 1985
(Hosted by Prof. H. Seliger).
6.
Centre for
Crystallographic Research, Roswell Park Memorial
Institute, Buffalo, USA, August 1985 (Hosted by
Prof. R. Parthasarathy).
7.
Dept. of Biophysics and
Dept. of Human Genetics, University of Colombia,
N.Y. USA, Sept. 1985 (Hosted by Prof. C. R. Cantor).
8.
Dept. of Biology,
Massachusetts Institute of Technology, Cambridge,
USA, Sept.1985 (Hosted by Prof. A. Rich).
9.
Chromosoma Lecture,
Institute of Molecular Biology, USSR Academy of
Sciences, Moscow May 1988 (Hosted by Acad. A. D.
Mirzabekov).
10.
Institute of Molecular
Genetics, USSR Academy of Sciences, Moscow May 1988
(Hosted by Prof. Frank Kamaenestkii).
11.
Dept. of Biochemistry,
Tufts University, Boston, USA June 1989 (Hosted by
Prof. B.D.Stollar).
12.
Dept. of Biology,
Massachusetts Institute of Technology, Cambridge,
USA June 1989 (Hosted by Prof. A. Rich).
13.
Symposium speaker, 6th
Conversation in Biomolecular Stereodynamics, Albany,
N.Y. USA, June 1989.
14.
Invited speaker, 2nd
International symposium of Protein Structure
Functions, University of Karachi, Pakistan, December
1989.
15.
Dept. of Biology,
Massachusetts Institute of Technology, Cambridge,
USA, July, 1990. (Hosted by Prof. A. Rich)
16.
Dept. of Genetics,
University of Washington, Seattle, USA, Aug 1990
(Hosted by Prof. Stanley Gartler).
17.
Invited speaker,
International Symposium on “Synthetic
Oligonucleotides: Problems and Frontiers of
Practical Application”. Shemyakin Institute, Moscow,
June 1991.
18.
Institute of Molecular
Biology, USSR Academy of Sciences, Moscow, June 1991
(Hosted by Acad, A.D. Mirzabekov).
19.
Institute of Molecular
Genetics, USSR Academy of Sciences, Moscow, June
1991 (Hosted by Prof. Frank Kamaenestkii).
20.
Institute of
Cytogenetics, USSR Academy of Sciences, Leningrad
June 1991.
21.
Symposium speaker, 8th
Conversation in Biomolecular Stereodynamics, Albany,
New York, USA 1993.
22.
Dept. of Biophysics,
University Paris Nord, Paris, France, June 1993
(Hosted by Prof. C. Helen).
23.
Dept. of Biophysics,
Museum National D’Histoire Naturelle, Paris, France,
1993 (Hosted by Prof. C. Helene).
24.
Dept. of Chemistry, New
York University, New York, USA, 1993 (Hosted by
Prof. N.R. Kallenbach).
25.
Dept. of Molecular
Biology, National Institute of Health, Maryland,
USA, 1993 (Hosted by S. Adhya).
26.
Dept. of Chemistry,
University of Rutgers, New Jersey, USA, 1993 (Hosted
by Prof. Wilma Olson).
27.
Dept. of Biology, MIT,
Cambridge, Boston, USA, 1993 (Hosted by Prof. A.
Rich).
28.
Dept. of Human Genome
Centre, Boston University, Cambridge, USA, 1993
(Hosted by Prof. Charles R. Cantor).
29.
Invited speaker, 2nd
Indo-Japan Workshop and ACT IV meeting Japan, March
1996.
30.
National Institute of
Genetics, Mashima, Japan, March 1996 (Hosted by
Prof. T. Gojobori).
31.
Banyu Tsukuba Research
Institute, Tsukuba, Japan, March 1996 (Hosted by
Prof. Susuma Nishimura).
32.
Invited speaker, “Human
Genome Treaty Symposium, Berlin, Germany, October
1996.
33.
Institute of Human
Genetic, Berlin, Germany, October 1996 (Hosted by
Prof. Karl Sperling).
34.
Institute for
Kristallagraphie, Germany, October 1996 (Hosted by
Prof. W. Saenger).
35.
Max-Planck Inst. fur
Biophysical Chem, Germany, October 1996 (Hosted by
Prof. T.M. Jovin).
36.
Max-Delbruck Centre for
Molecular Medicine, Berlin, Germany, (Hosted by Dr.
U. Heinmann).
37.
Genetique Medicale Et
Development, Marseille, France, October 1996 (Hosted
by Prof. M. Fontes).
38.
FAOBMB 14th
Symposium, University of Otago, Dunedin, New
Zealand, November 28th –December 3rd
1999.
39.
Invited lecture,
Institute of Biomedical Research, University of
Sydney, December 1999.
40.
Delivered a talk at
UNESCO on “Genome Research & IPR” 13th
June, 2001.
41.
Delivered a talk at
Vienna on “Genome Research & Patenting in Developing
Countries” on 22nd November 2001.
42.
Delivered a talk at
Geneva on Rights & Issues relating to the “Genetic
Resources of the Developing Countries” on 24th
January 2002.
43.
Delivered a talk in
“Disease Genomics Workshop” at HUGO meeting at
Shanghai, April 2002.
44.
Invited Lecture at
Beijing in Genome Centre on April 2002.
45.
Delivered an invited
Lecture in Bioscience Asia meeting at Taiwan on
“Functional Genomics in Silico” on 22nd
May, 2002.
46.
Delivered lecture during the India
Day Celebrations at Royal Society, London on
December 11th,
2002.
47.
Delivered talk on
“Variation and Conservation Balancing Act in Genome:
Comparative Genomics Approach” at RIKEN, Japan on 22nd
April, 2004.
48.
Delivered talk on
“BT-IT Bridges over Genome River: Functional
Genomics to System Biology” at India Biotechnology
Seminar in Japan on 23rd April, 2004.
49.
Delivered a talk “SNPs,
Chips, Informatics and Predictive Medicine” at Swiss
Federal Institute of Technology Lausanne (EPFL),
Lausanne, Switzerland on 6th October
2004.
50.
Delivered talk on
“Variation and conservation: a balancing act in
genome” at the Sino-India Workshop on genome
Informatics at Hangzhou, China on 30th October,
2004.
51.
Delivered a talk at the
Pan Asian SNP Consortium meeting held at Singapore
on 18th November entitled “A brief comment on Pan
Asian SNP Project”.
52.
Delivered invited talk
at the 17th FAOBMB/IUBMB/A-IMBN Meeting entitled
“Comparative Proteomics in silico for drug target
identification” held at Bangkok, Thailand from 22nd
to 26th November, 2004.
53.
Delivered invited
lecture at the Asia Biotech Forum 2005 at Kuala
Lumpur titled “Private-Public Partnership in
Genomics & Bioinformatics: An Indian Perspective” on
4th February 2005.
54.
Delivered inaugural and
keynote address at the Workshop “Health of
Populations in the Mediterranean in the post genomic
era” in Tunisia on 4th March, 2005
entitled “Predictive Medicine and Health Research in
the Post Genomic Era”.
55.
Delivered an invited
talk at the HGM 2005, held at Kyoto on 19th
April, 2005 entitled “Conservation and Variation: A
Balancing Act in the Genome”.
56.
Delivered talk on
"Identification of Evolutionarily Conserved
Polypeptide folds by Comparative Genomics" at
Institute of Evolution, University of Haifa, Israel
on 29th May, 2005.
57.
Delivered talk entitled “Transforming CSIR to
Council for Scientific & Innovative Research” at
the Workshop on “Promoting and
Facilitating Innovation driven new ventures” in
Haifa, Israel on 31st May, 2005.
58.
Delivered the BIGROC Lecture at
Weizmann Institute of Science,
Rehovot, Israel on 2nd June, 2005
entitled “Conservation and Variation: A Balancing
Act in the Genome”.
59.
Delivered an invited talk at session on Comparative
genomics in the Albany 2005: The 14th
Conversation at Albany, NY, USA entitled
“Conservation and Variation: A Balancing Act in the
Genome”.
60.
Delivered an invited talk at the CII session ‘Enabling
Global Drug Discovery by Leveraging Information
Technology prowess in India’
at the BIO 2005 in Philadelphia, USA on 21st June
2005 entitled "Identification of Novel Drug Targets
using In Silico Comparative Genomics and System
Biology Approach".
61.
Delivered an invited
talk entitled "Comparative Genomics and pathway
modeling approaches towards Novel Drug Target
Identification" at the India session at the 2005
International Symposium on Computational Biology &
Bioinformatics (ISCBB2005) in Tokyo, Japan on 28th
October, 2005.
62.
Invited to co-chair the
session on "Developing the Proper Context for
Systems Biology" and deliver a talk entitled “Need
for High Input Biology for Systems Biology Approach”
at the meeting on Integrative Systems Biology for
Health -TRANSCRIPTOME 2005 at Shanghai on 9th
November, 2005.
63.
Delivered a
talk at the Taiwan-India Joint Symposium on
Functional Genomics at Taipei, Taiwan on 3rd-4th
March, 2006 titled Comparative Genomics and Pathway
Modelling approaches towards Novel Drug Target
Identification.
64.
Co-chaired and
delivered a talk at the session “Biobank” at the
HUGO Asia Pacific Meeting held at Taipei, Taiwan
from 6th-10th March, 2006
titled ‘Indian
Genome Variation Database: From a Disease
Perspective’.
65.
Delivered an invited
talk at the Department of Bioorganic Chemistry at
Uppsala University on 29th May, 2006
entitled “Conservation and Variation in the Genome:
A Balancing Act”.
66.
Chaired the
Bioinformatics Workshop at HGM 2006 at Helsinki,
Finland on 1st June, 2006 and delivered
Workshop overview entitled “Genome Informatics:
Opportunities and Challenges ahead”.
67.
Delivered a talk at the
EU Workshop on International Cooperation in
Functional Genomics Research during the HGM 2006 at
Helsinki, Finland on 3rd June, 2006
entitled “Functional Genomics: Indian Initiative”.
68.
Delivered an invited
talk at the Human Variome Project meeting at the
Session on “Relevance
to the Emerging World” at
Melbourne, Australia on 22nd June, 2006
entitled “Genotype to Phenotype Correlation (G2P)
for Complex Disorder”.
69.
Delivered an invited
talk at the session entitled Genomics in Asia during
the 2006 International Conference on Genomics in
Hangzhou, China on 25th October, 2006 titled “Genome
Variation & Disease Genomics: the Indian
Initiative”.
70.
Delivered lectures at
the Pan Asian SNP Data Analysis and Manuscript
Writing Meeting at Singapore entitled “Pan Asian SNP
Initiative: An Anthropological Perspective” and
“Structural Polymorphism in Indian Population” on 9th
and 11th November, 2006 respectively.
71.
Chaired the
Bioinformatics Workshop at HGM 2007 at Montreal,
Canada on 22nd May, 2007 and delivered
Workshop overview entitled “Genomics Research:
What’s Next”?
72.
Delivered an invited
talk a the National Cancer Center, National
Institutes of Health, Bethesda titled “MicroRNA
mediated regulatory networks: an in-silico approach”
on 31st May, 2007
73.
Delivered an invited
talk at the McKusick-Nathans Institute of Genetic
Medicine, Johns Hopkins University, Baltimore titled
“Indian Genome Variation database from Complex
Disease Perspective” on 1st June, 2007.
In addition to these, Prof. Samir K.
Brahmachari has delivered several lectures at
various other laboratories and academic
institutions.
Complete List of Publications
A.
Polypeptides and Proteins
1.
Polypeptide models of
Collagen. I. Solution properties of (Gly-Pro-Sar) and (Gly-Sar-Pro)n.
V. S. Ananthanaryanan, Samir K. Brahmachari, Rao,
S. Rapaka and R. S. Bhatnagar.
Biopolymers (1976) 15(4): 707
2.
Polypeptide models of
Collagen, II. Solution properties of (Pro-Gly-Phe) n.
Samir K.
Brahmachari, V.S. Ananthanaryanan, Rao, S. Rapaka
and R.S. Bhatnager.
Biopolymers (1978) 17(9): 2096
3.
Structural investigations
on Poly-4-hydroxy-L-proline I.Theoretical studies.
M. Bansal, Samir K. Brahmachari
and V. Sasisekharan.
Macromolecules (1979) 12: 19
4.
Structural investigations
on Poly-4-hydroxy-L-proline. II. Physico-chemical and
X-ray studies. Samir K. Brahmachari, M. Bansal,
V.S.Ananthanaryanan, V. Sasisekharan.
Macromolecules (1978) 12: 23
5.
Conformational criteria for
the enzymatic hydroxylation of proline in collagen.
Samir K.
Brahmachari and V.S.Ananthanaryanan.
Curr. Sci.(1978) 47: 107
6.
b-turns in nascent
procollagen are sites of po7st translational enzymatic
hydroxylation of proline. Samir K. Brahmachari
and V.S.Ananthanaryanan.
Proc. Natl. Acad, Sci. USA, (1979) 76:
5119
7.
Vacuum Ultraviolet Circular
dichroism spectrum of
b-turn
in solution.
Samir K. Brahmachari,
V.S.Ananthanaryanan, J. Brahms, S. Brahms, Rao, S.
Rapaka
and R.S. Bhatnagar.
Biochem. Biophys. Res. Comm. (1979) 86:
605
8.
b-turn conformation of
N-acetyl-Pro-Gly-Phe-OH in crystal and solution and its
relevance to collagen.
V.S.Ananthanaryanan, Samir K.
Brahmachari and M. Vijayan.
Federation Proc. (1980) 39: 1788
9. Crystal structure and solution
studies on N-acetyle-Pro-Gly- Phe-OH.
Samir K. Brahmachari,
V.S.Ananthanaryanan, T.N. Bhat, V. Sudhakar, M. Vijayan,
Rao, S. Rapaka and R.S. Bhatnagar.
J.Amer. Chem. Soc. (1981)
103: 1703
10.
Proline containing
b-turns
in –peptides and proteins. I. Physico-chemical studies
on N-acetyl- Pro-Gly-X-OH tri- peptides
Samir K. Brahmachari,
V.S.Ananthanaryanan, Rao, S. Rapaka and R.S.Bhatnagar.
Biopolymers (1982) 21: 1208.
11.
Proline containing
b-turns
in peptides and proteins. II. Analysis of globular
protein data.
V.S.Ananthanaryanan, Samir
K. Brahmachari and N.Pattabiraman.
Arch. Biochem. Biophysics (1984)
232: 482
B.
Nucleic Acids and Chromatin
12.
Site and role of the
N-terminal fragment of the nucleosomal core histonesin
their bind to deoxyribonucleic acid as determined by
vibrational spectroscopy.
M. couppez, Santiere, Samir K.
Brahmachari, J. Brahms, J. Liquier and E.
Taillandier.
Biochemistry (1980) 19: 3358
13. B to Z transition in a DNA fibre: The question
of handedness of the duplex.
V. Sasiskharan and Samir K.
Brahmachari.
Curr. Sci. (1981) 50: 1
14.
Conformational flexibility
of DNA: A theoretical formalism and a few practical
applications.
V.Sasisekharan, Manju Bansal,
Samir K. Brahmachari and Goutam Gupta.
Biomolecular sterreodynamics,
ed. R.H. Sarma, Adenine Press, N.Y. (1981) 1: 123
15.
Conformation of DNA in
chromatin reconstituted from poly(dA-dT) and the cor
histones.
S. Brahms, Samir K. Brahmachari,
N. Angelier and J.G.Brahms.
Nucleic Acids Res. (1981) 9: 4879
16.
B to Z transition in
DNA and its biological implications.
Samir K.Brahmachari,
Latha P. Kadalayil, Majumdar, K. and Parnaik, V.K.
Proceedings of INDO-FRG
seminar, BARC, (1983) : 106
17.
Critical cation
balance in B«Z
transition; Role of Li+.
Ramesh N. and Samir K.
Brahmachari.
FEBS lett. (1983) 164: 33
18.
Temperature dependent
ZÞB
transitions in Poly (dG-dC).
Latha P. Kadalayil, Majumdar,
K. and Samir K. Brahmachari.
Curr. Sci, (1983) 52: 907
19.
X-ray diffraction
studies on Mycobacterium Smegmatis DNA.
Rajagopalan, M., Samir K.
Brahmachari, V. Sasisekharan and Srivastava R.
Biopolymers (1983) 22(7):
1633
20.
Structural
organization of the meotic prophase chromatin in the rat
testis.
Rao B.J., Samir K.
Brahmachari and Rao M.R.S.
J.Biol.chem, (1983) 258:13478
21.
A novel structural
transition in poly (dG-Me5dC) :Z«B«Z.
Latha P.Kadalayil and
Samir K. Brahmachari.
FEBS lett. (1985) 182:315
22.
Left handed DNA in
synthetic and topologically constrained form V DNA and
its implications in protein recognition.
Shouche,Y.S., Latha
P.Kadalayil, Ramesh N., Majumder K., Mandyan V.
and
Samir K. Brahmachari.
Proc. Int symp. Biomol. Struct
Interactions,Suppl.J.Biosciences (1985) 8: 563
23.
Poly (dG-dC) in the Z-form
inhibits E.Coli DNA polymerase I and AMV DNA polymerase
activity.
Samir K. Brahmachari,
Ramesh N., M.R.Das and Veena K.Parnaik.
Biochemistry Int. (1985) 11:
281
24. B to Z transitions in DNA and their
biological implications.
Latha P.Kadalayil and Samir K.
Brahmachari.
J.Scientific & Industrial
Res. (1986) 45: 521
25. Sequence dependence and role of 5'-phosphate
in B to Z transition.
Majumder K., Samir K. Brahmachari
and V.Sasisekharan.
FEBS lett.
(1986) 198: 240
26.
Use of volatile buffer at ambient
temperature:Versatile approach to the purification of
self complementary synthetic deoxyribonucleotides by
reverse phase high performance liquid chromatography.
Majumder
K.,Latha P.Kadalayil and Samir K.Brahmachari.
J.Chromatography (1986) 355: 328.
27.
Recognition of B and Z forms of DNA by
E.Coli DNA polymerase.
Ramesh
N.,Shouche Y.S. and Samir K.
Brahmachari.
J.Mol.Biol. (1986) 190: 635
28.
DNA structural variability as a factor in
gene expression and evolution.
Conrad
M.,Samir K. Brahmachari and V.
Sasisekharan.
Biosystems (1986) 19: 123
29.
Sequences that adopt non B-form
conformation in form V DNA as probed by enzymatic
methylation.
Samir K.
Brahmachari,
Shouche Y.S., Charles R. Cantor and M.McClelland.
J.Mol.Biol. (1987) 193: 201
30.
Synthesis and purification of
Oligodeoxyribonucleotides:A modified approach.
Kumud
Majumder, Latha P.Kadalayil and Samir K. Brahmachari.
Curr.
Sci. (1987) 56: 693
31.
Torsional stress, Unusual DNA structures;
and Eukaryotic gene expression.
C. R.
Cantor, S. Bandopadhaya, Samir K. Brahmachari,
C.F. Hui, M.McClelland, R. Morse and C. L. Smith.
“Unusual
DNA structure”; Ed. R.D. Wells and S.C. Harvey.
Springer-Verlag, New York, (1988).
32.
Sequence specificity of Z-DNA formation in
Oligonucleotides.
Latha
P.Kadalayil, Kumud Majumder, R. K. Mishra and Samir
K. Brahmachari.
Biochemistry Int. (1988) 17: 121
33.
Interruption of (CG)n sequences by GG, TG nad CA need
not prevent B to Z transition in solution.
R.K.Mishra,
Latha P. Kadalayil and Samir K. Brahmachari.
Nucleic
Acids Res. (1988) 16: 4651
34.
Synthesis of novel polynucleotide:
Potential R-L model.
R.K.Mishra and Samir K.
Brahmachari.
Curr.
Sci. (1988) 57: 574
35.
Dynamic nature of B to Z transition: Role
of DNA supercoiling and Z-DNA binding protein.
N. Ramesh
and Samir K. Brahmachari.
Ind. J.
Biochem. Biophys. Silver Jubilee issue (1988) 25: 542
36.
Sequence criteria for Z-DNA formation: Studies on poly
d(ACGT).
Kumud
Majumder, Rakesh K. Mishra, Manju Bansal and Samir K.
Brahmachari.
Nucleic
Acids Res. (1989) 17: 450
37.
Sequence specificity in supermine induced structural
changes in CG-oligomers.
Kumud Majumder and Samir K. Brahmachari.
Biochemistry In., (1989) 18: 455
38.
Structural alteration from non-B to
B-form could reflect Dnase I hypersensitivity.
N.Ramesh
and Samir K. Brahmachari.
J.Biomol.Struc. Dynamics (1989) 6: 899
39.
Zintrons in rat alpha-Lactalbumin gene.
G.Meera, N.Ramesh and Samir K. Brahmachari.
FEBS lett
(1989) 251: 245
40.
Preparation of Megabase DNA from adult
insects and mammalian spleen for pulse field gel
electrophoresis.
Vani
Brahmachari, R.Nagasuma and Samir K. Brahmachari.
J.
Genetics (1989) 68: 185
41.
Unusual DNA structures:Sequence
requirements and role in transcriptional control.
Samir K.
Brahmachari,
N. Ramesh,Yogesh S. Souche, Rakesh K.
Mishra, Rajesh Bagga and G. Meera.
Structures & Methods, Vol 2,
Eds.R.H.Sarma & M.H. Sarma.
Adenine
press (1990)
42.
DNA
duplex with a potential to change handedness after every
half a turn.
Samir K.
Brahmachari,
Rakesh
K.Mishra, Rajesh Bagga and N.Ramesh
Nucleic Acids Res. (1989) 17: 7273
43.
Role of
Environment in the Interaction of Nonintercalators with
Z-DNA.
K.Ekambareswara Rao, N.Ramesh, D.Chaudhary, Samir K.
Brahmachari and
V.Sasisekharan
Journal of Biomolecular Structure & Dynamics (1989) 7:
335
44.
Probing
of unusual DNA structures in topologically constrained
from V DNA:Use of restriction enzyme as a structural
probe.
ShoucheY.S., N.Ramesh and Samir K. Brahmachari
Nucleic Acids Res. (1990) 18: 267
45.
Supercoil induced unusual DNA structures
as transcriptional block.
Rajesh Bagga, N.Ramesh and
Samir K. Brahmachari
Nucleic
Acids Res. (1990) 18: 3363
46.
Z-DNA Binding Protein Mediated
Stabilization of the Z-conformation.
Samir K.
Brahmachari, Eugenia T.Paulus, N.Krishnamachary
and N.Ramesh
In
Protein Structure-Function (1990), Ed.Zaidi, Abbasi &
Smith,TWEL Publishers,135
47.
A novel
approach to design cis-acting DNA structural elements
for regulation of gene expression in vivo.
P.S.Sarkar,R.Bagga,P.Balagurumoorthy and Samir K.
Brahmachari
Curr.
Sci. (1991) 60: 586
48.
Distribution of simple repetitive (TG/CA)n and (CT/AG)n
sequences in human and rodent genome.
Jalaj
Tripathi and Samir K. Brahmachari
Journal
of Biomolecular Structure & Dynamics. (1991) 9:387
49.
Synthetic gene design to investigate the role of
cis-acting DNA structural elements in regulation of gene
expression in vivo.
Samir K.
Brahmachari,
P.S.Sarkar, P.Balagurumoorthy, P.Burma and R.Bagga
Nucleic
Acids Res., Symp. Series (1991) 24: 163
50.
Hairpin
and parallel quartet structures for telomeric sequences.
P.Balagurumoorthy, Samir K. Brahmachari,
Debasis Mohanty, Manju Bansal and V.Sasisekharan
Nucleic
Acids Res. (1992) 20: 4061
51.
Intramolecular triplex potential sequence within a gene
down regulates its expression in vivo.
P.S.Sarkar
and Samir K. Brahmachari
Nucleic
Acids Res (1992) 20: 5713
52.
Genome Analysis I: A new approach for
visualization of sequence organization in genomes.
P.K.Burma, Alok Raj, Jayant K.Deb and
Samir K. Brahmachari
Journal
of Biosciences (1992) 17: 395
53.
Polypurine-polypyrimidine sequences adopt
unwound structure in pBR322 from V DNA as probed by
single-hit analysis of HpaII sites.
R.Bagga
and Samir K. Brahmachari
Journal
of Biomolecular Structure & Dynamics (1993) 10: 879
54. Chaos game representations of
similarities and differences between genomic sequences.
S.Baranidharan, B.Sankaranarayanan and
Samir K. Brahmachari
International Journal of Genome Research (1994) 1: 309
55. Intramolecular DNA triple
helix and regulation of gene expression.
Samir K.
Brahmachari
and P.S.Sarkar
Structural Biology: State of Art 1993, Vol 2, Eds.
R.H.Sarma and M.H.Sarma, Adenine press (1994)
56.
CA/TG sequence at the 5' end of oligo
a-tracts strongly modulates DNA curvature.
Akhilesh
K.Nagaich, D.Bhattacharya, Samir K. Brahmachari
and Manju Bansal
J.Biol.Chem (1994) 269: 7824
57.
Structure and Stability of Human
Telomeric Sequence.
P.Balagurumoorthy and Samir K.
Brahmachari
J.Biol.Chem (1994) 269: 21858
58. Synthetic gene design for
modulation of gene expression in vivo.
Samir K.
Brahmachari,
Partha S.Sarkar, P.K.Burma, U.S.Shaligram and
S.S.Pataskar
Proc. of
the Ranbaxy Sym. On Mol. Genetics and Gene
therapy,(1995), 85-97
59.
Functional significance of simple
repetitive sequences in the genome.
Samir K.
Brahmachari, G.Meera,Partha S.Sarkar,
P.Balagurumoorthy, J.Tripathi, S.Raghavan, U.S.Shaligram
and S.S.Pataskar
Electrophoresis (1995) 16: 1705-1714
60.
Analysis of CAG/CTG triplet repeats in
the human genome: Implication in transcription factor
gene regulation.
Rachna Bhandari and
Samir K. Brahmachari
J.
Biosci. (1995) 20: 613
61.
Intra and interloop interactions in
the folded G quartet structure of Oxytricha telomeric
sequence.
P.Balagurumoorthy and Samir K.
Brahmachari
Ind.J.Biochem.Biophys. (1995) 32: 385
62.
Polypurine/polypyrimidine
sequences as cis acting transcriptional regulators.
Samir K.
Brahmachari,
Partha S.Sarkar, Sowmya Raghavan, Malthy Narayan and
Amit K.Maiti
Gene (1997) 190: 17
63.
Positional preferences of
polupurine/polypyrimidine sequences in the genome of
S.cerevisiae:Implications for cis-regulation of gene
expression.
Sowmya
Raghavan, Pradeep K.Burma and
Samir K. Brahmachari
Journal
of Molecular Evolution (1997) 45: 485-498
64.
Human genome studies and
intellectual property rights: Whither national interest?
T R Sivaramjani and
Samir K. Brahmachari
Current
Science (1997) 72: 708
65. International Collaboration in
genetic research.
S. Chatterjee, Samir K. Brahmachari,
S Jain, P. Majumder and T Reich.
Nature
Genetics (1997) 15: 124
66. Variation at the MJD locus in
the major psychoses.
Q.Saleem,
M.Vijayakumar, M.Mulsuddi, N.Chowdhary, S.Jain and
Samir K. Brahmachari
Am.J.Med.Genet. (1998) 81(5): 440-442
67.
Correlation of Clinical Profile of Mytonic dystrophy
with CTG repeats in Mtotonin Protein kinase gene.
M.Gourie-Devi, J.Ray Chaydhari, Anisya Vasanth, Q.Saleem,
Mousumi Mutsuddi, Meera Gopinath, P.S.Sarkar and
Samir K. Brahmachari
Ind.J.Med.Res. (1998) 107: 187-196
68.
Investigating the role of Trinucleotide
repeats in schizophrenia and bipolar disorder.
Quasar
Saleem, Sanjeev Jain and Samir
K. Brahmachari
In the
Proceedings of 5th Annual Symp., Ranbaxy Science
Foundation. On Molecular Intervention in Disease (1998),
85-89
69.
Peptide models for inherited
neurodegenerative disorders: conformation and
aggregation properties of long polyglutamine peptides
with and without interruptions
Deepak
Sharma, Sunita Sharma, Santosh Pasha and
Samir K. Brahmachari
FEBS.
Lett. (1999) 456(1):181-185.
70
The multitude of ‘omics’ and ‘omes’:
Evolution of scientific terms in molecular biology in
the new millennium.
Srinivasn Ramachandran, Debasis Dash,
Samir K. Brahmachari
Current
Science, (1999) 77(7): 846-847
71.
Polypurine/polypyrimidine repeats in
complete bacterial genomes: Preference for
polypurine repeats in protein-coding regions (1999).
Sowmya
Raghawan, Ramesh Hariharan and
Samir K. Brahmachari
Gene
(2000) 242: 275-283
72.
Association analysis of CAG repeats at
the KCNN3 locus in Indian patients with Bipolar disorder
and Schizophrenia.
Quasar
Saleem, V.S. Sreevidya, J. Sudhir, J. Vijaya Savithri,
Y. Gowda, V. Benegal, Chandrika B. Rao, Partha P.
Majumder, Anuranjan Anand, Samir K. Brahmachari
and Sanjeev Jain
Am.J.Med.Genet. (2000) 96, 744-748.
73.
Molecular analysis of autosomal dominant
hereditary ataxias in the Indian population: High
frequency of SCA2 and evidence for a common founder
mutation.
Quasar
Saleem, Shweta Choudhry, Mitali Mukherji, Leena Bashyam,
M.V.Padma, Amber Chakravarthy, M.C.Maheshwari, Satish
Jain and Samir K. Brahmachari
Human
Genetics (2000) 106: 179-187.
74.
Association analysis of 5HT transporter
gene in bipolar disorder in the Indian population.
Q.
Saleem, S. Ganesh, M. Vijaykumar, Y.C.J.Reddy., Samir
K. Brahmachari, Sanjeev Jain
Am. J.
Med. Genet. (2000) 92(2): 170-172
75. Probing the polyglutamine
puzzle in neurological disorders.
Samir K.
Brahmachari
, Deepak
Sharma , Sharma S, Santosh Pasha, Sen S, Quasar Saleem Q
FEBS
Lett. (2000) 472(1): 167-168
76. Association of CAG repeat Loci on Chromosome 22
with Schizophrenia and Bipolar Disorder.
Quasar
saleem, Debasis Dash, Charu Gandhi, Anupam Kishore,
Vivek Benegal, Tessi Sherrin, Odity Mukerjee, Sanjeev
Jain and Samir K. Brahmachari
Mol.
Psychiatry (2001) 6(6): 694-700
77.
Progressive Myoclonus Epilepsy [EPM1]
repeat d(CCCCGCCCCGCG)n forms folded hairpin structures.
Shashank
S. Pataskar, Debasis Dash and
Samir K. Brahmachari
J.
Biomol. Struct. Dynamics (2001)
19(2):293-305.
78.
Intramolecular I-motif structure at
acidic pH for progressive Myoclonus Epilepsy [EPM 1]
repeat d (CCCCGCCCCGCG)n.
Shashank
S. Pataskar, Debasis dash and
Samir K. Brahmachari
J.
Biomol. Struct. Dynamics (2001)
19(2):307-313
79.
The polyglutamine motif is highly
conserved at the clock locus in various organisms and is
not polymorphic in humans.
Quasar
Saleem, Anuranjan Anand, Sanjeev Jain and
Samir K. Brahmachari
Human
Genetics (2001) 109(2): 136-142
80.
CAG repeat instability at SCA2
Locus: anchoring CAA interuptions and linked single
nucleotide polymorphism.
S. Choudhry, M.
Mukerji, A. K. Srivastava, S. Jain,
S. K. Brahmachari
Hum. Mol. Genet. (2001)
10(21):2437-2446
81.
Molecular and Clinical Correlation in
five Indian families with Spinocerelellar Ataxia 12.
Achal K.
Srivastava, Shweta Choudhry, Musuwadi S. Gopinath,
Sanghamitra Roy, Manjari Tripathi, Samir K.
Brahmachari, and Satish Jain
Annals
of Neurology (2001) 50 (6) : 786-800
82.
Poly
purine.pyrimidine sequences upstream of the
beta-galactosidase gene affect gene
expression in Saccharomyces cerevisiae.
Maiti AK,
Brahmachari SK
BMC Mol Biol (2001) 2(1):11
83.
A clinical study of patients with
genetically confirmed Huntington's disease from India.
Murgod UA, Saleem Q, Anand A,
Brahmachari SK, Jain S, Muthane UB
J Neurol Sci (2001)
15;190(1-2):73-8
84.
Study of the Single Nucleotide
Polymorphism (SNP) at the palindromic sequence of
Hypersensitive Site (HS)4 of the human ß -globin Locus
Control region (LCR) in Indian
Population.
Ritushree
Kukreti, Chandrika B-Rao, Swapan Kr Das, Madhusnata De,
Geeta Talukder, Flavian Vaz, I. C. Verma,
Samir K. Brahmachari
Am. J.
Hemat.
(2001) 69:77-79
85.
ACE insertion allele in relation to high altitude
adaptation.
M. A. Qadar Pasha, AP Khan, Ratan Kumar, SK Grover, T
Norboo, KK Srivastava, W. Selvamurthy,
SK Brahmachari
Annals of
Human Genetics
(2001): 65: 531-536
86. Expanding colonies and expanding
repeats.
Quasar Saleem, Uday Murgod,
Uday Muthane, Anuranjan Anand, Inder C Verma,
Samir K. Brahmachari,
Sanjeev Jain.
Lancet (2002) 9; 359(9309):
895-6.
87. Functional Genomics & DNA chips.
Samir K. Brahmachari
Appl Biochem Biotech (2001)
96/1-3: 9-12
88. Genome-wide expression profile of
RNA polymerase II subunit mutant of yeast using
microarray technology.
Beena Pillai,
Samir
K. Brahmachari
and PP. Sadhale
Current Science, (2001) 81,5,
574-578
89.
Angiotensin converting enzyme I/D polymorphism in
ethnically different populations of India.
M A.
Qadar Pasha, AP Khan, Ratan Kumar, SK Grover, KK
Srivastava, W. Selvamurthy, SK
Brahmachari
J. Biosci. (2002) 27: 67-70
90.
Molecular analysis of Huntingtons disease
and linked polymorphisms in the Indian population.
Q. Saleem, S.Roy, U.Murgood, R.Saxeena, I.C. Verma,
A.Anand, U.Muthane, S.Jain, S.Jain,
S.K.Brahmachari
Acta Neurol Scand. 2003 Oct; 108(4): 281-286.
91.
Whole Genome Expression Profiles of
Yeast RNA Polymerase II Core Subunit, Rpb4, in Stress
and Nonstress Conditions.
Pillai B, Verma J, Abraham A, Francis P, Kumar Y,
Tatu U, Brahmachari SK, Sadhale PP.
J. Biol
Chem. (2003) 278(5): 3339-46.
92.
A novel complexity measure for comparative analysis of
protein sequences from complete genomes.
Nandi T, Dash D, Ghai R, Rao CB, Kannan K,
Brahmachari SK, Ramakrishnan C, Ramachandran
J.
Biomol Struct Dyn. (2003) 20(5): 657-68.
93.
Role of histidine interruption in
mitigating the pathological effects of long
polyglutamine stretches in SCA1: A molecular approach.
Sen S., Dash D., Pasha S., and
Brahmachari SK
Protein Science (2003) 12(05):
953-962
94.
Non-random distribution of Alu elements in genes of various
functional categories: insight from analysis of human
chromosomes 21 and 22.
Deepak Grover, Partha P. Majumder , Chandrika B. Rao,
Samir K. Brahmachari , Mitali Mukerji
Molecular Biology and Evolution 2003 Sep;
20(9): 1420-4. Epub 2003 Jun 27.
95.
(TG:CA)(n) Repeats in Human Housekeeping Genes.
Sharma VK, Rao CB, Sharma A,
Brahmachari SK, Ramachandran S.
J Biomol Struct Dyn. 2003 Oct; 21(2):303-10.
96.
Arterial oxygen saturation under hypoxic environment of
high altitude associates with routine physical
activities of natives.
M. A. Qadar Pasha, K. S.
Kocherlakota, A. P. Khan, T. Norboo, S. K. Grover, M. A.
Baig, W. Selvamurthy and S. K.
Brahmachari
Current Science 2003;
85(4):502-506
97.
Association of high-altitude systemic hypertension with the
deletion allele-of the angiotensin-converting enzyme
(ACE) gene.
Kumar R, Qadar Pasha MA, Khan AP, Gupta
V, Grover SK, Norboo T, Srivastava KK, Selvamurthy W,
Brahmachari SK
Int J Biometeorol 2003; 48(1):10-14
98.
Hairpin-duplex equilibrium reflected in
the A-->B transition in an undecamer quasi-palindrome
present in the locus control region of the human
beta-globin gene cluster.
Kaushik M, Kukreti R, Grover
D, Brahmachari SK, Kukreti S.
Nucleic Acids Res. 2003 Dec; 1;
31(23):6904-15
99.
Recognition and analysis of protein coding
genes in severe acute respiratory syndrome associated
coronavirus.
Sharma R, Maheshwari JK, Prakash T, Dash
D, Brahmachari SK.
Bioinformatics. 2004 May;
20(7): 1074-80
100.
Alu repeat analysis in the complete human
genome: trends and variations with respect to genomic
composition.
Grover D, Mukerji M, Bhatnagar
P, Kannan K, Brahmachari SK.
Bioinformatics. 2004 Apr;
20(6): 813-17
101.
A nonsense mutation in the synaptogyrin 1
gene in a family with schizophrenia.
Verma R, Chauhan C, Saleem Q,
Gandhi C, Jain S, Brahmachari
SK.
Biol Psychiatry. 2004 Jan 15;
55(2):196-9
102.
CoPS: Comprehensive Peptide Signature
Database.
Tulika Prakash, Mamta Khandelwal, Dipayan Dasgupta, Debasis Dash*,
Samir K.
Brahmachari.
Bioinformatics. 2004 Nov 1; 20(16):2886-8
103.
Evolution and distribution of RNA
polymerase II regulatory sites from RNA polymerase III
dependent mobile Alu elements.
Ravi Shankar, Deepak Grover, Samir K.
Brahmachari and Mitali Mukerji
BMC Evolutionary Biology 2004, 4(1):37 (4
Oct 2004).
104.
Clusters of proteins in archaeal and
bacterial proteomes using compositional analysis.
Nandi T, Brahmachari SK, Kannan K,
Ramachandran S.
In Silico Biol. 2004;4(4):573-91.
105.
Conformational Analysis of Invariant
Peptide Sequences in Bacterial Genomes.
Tulika Prakash, C.
Ramakrishnan, Debasis Dash and Samir K. Brahmachari*
J
Mol Biol. 2005 Feb 4; 345(5):937-55.
106.
Identification of a novel 45 repeat
unstable allele associated with a disease phenotype
at the MJD1/SCA3 locus.
Padiath QS, Srivastava AK, Roy S, Jain S, Brahmachari
SK.
Am. J Med Genet B Neuropsychiatr Genet. 2005 Feb5;
133(1):124-6
107.
Assessing natural variations in gene
expression in humans by comparing with
monozygotic twins using microarrays.
Sharma A, Sharma VK,
Horn-Saban S, Lancet D, Ramachandran S, Brahmachari
SK.
Physiol
Genomics. 2005 Mar 21; 21(1):117-23.
108.
Comparative analysis of chromatin
landscape in regulatory regions of human
housekeeping and tissue specific genes.
Ganapathi M, Srivastava P, Das Sutar SK,
Kumar K, Dasgupta D, Singh GP, Brahmachari V,
Brahmachari SK.
BMC Bioinformatics. 2005 May 26; 6(1):126.
109.
Sharma VK, Brahmachari SK,
Ramachandran S.
(TG/CA)n repeats in human gene families: abundance and
selective patterns of distribution according to function
and gene length.
BMC Genomics. 2005 Jun 3;
6(1):83.
110.
Genomics and Functional Genomics
Mitali
Mukerji, Beena Pillai, Somdutta Sen and
Samir K. Brahmachari.
Textbook of Biotechnology, 2005, pp 1349-1409, Eds. Dr.
H.K.Das, Wiley Dreamtech Pvt. Ltd, Delhi.
111.
Ritushree Kukreti,
Pallav Bhatnagar, Chandrika B-Rao,
Simone Gupta, Babita Madan, Chinmoyee Das,
Randeep Guleria, Amita Umesh Athavale, Samir
Kumar Brahmachari & Balaram Ghosh.
2-adrenergic
receptor polymorphisms and response to salbutamol among
Indian asthmatics.
Pharmacogenomics. Jun 2005;
6(4): 399-410.
112.
R. Verma, M. Mukerji, D. Grover, C. B-Rao,
S. Das, S. Kubendran, S. Jain, S.K. Brahmachari.
MLC1 Gene Is Associated with Schizophrenia and
Bipolar Disorder in Southern India.
Biological Psychiatry. 2005;
58(1):16-22.
113.
Grover D,
Kannan K,
Brahmachari SK,
Mukerji M.
ALU-ring elements in the primate genomes.
Genetica. 2005
Jul;124(2-3):273-89.
114.
Manoj Hariharan, Vinod Scaria, Beena
Pillai, Samir K. Brahmachari.
Targets for human encoded
microRNAs in HIV genes.
Biochem Biophys Res Commun.
2005 Oct 7;337(4):1214-1218.
115.
The Indian Genome Variation Consortium
(158 authors).
S.K. Brahmachari
et.al.
The Indian Genome Variation
database (IGVdb): a project overview.
Hum Genet. 2005; 118: 1–11.
116.
Verma R, Kubendran S, Das SK, Jain S,
Brahmachari SK.
SYNGR1 is associated with schizophrenia
and bipolar disorder in southern India.
J Hum Genet. 2005;50(12):635-40.
117.
Ritushree Kukreti, Sudipta Tripathi,
Pallav Bhatnagar, Simone Gupta, Chitra Chauhan,
Shobhana Kubendran, Y.C. Janardhan Reddy, Sanjeev
Jain, Samir K. Brahmachari.
Association of DRD2 gene
variant with schizophrenia.
Neurosci Lett. 2006 Jan
9;392(1-2):68-71.
118.
Simone Gupta,
Sanjeev Jain,
Samir
K Brahmachari
&
Ritushree
Kukreti.
Pharmacogenomics: a path to
predictive medicine for schizophrenia.
Pharmacogenomics. 2006 Jan;7(1):31-47.
119.
Guzman MR,
Liquier J,
Brahmachari SK,
Taillandier E.
Characterization of parallel and
antiparallel G-tetraplex structures by vibrational
spectroscopy.
Spectrochim Acta A Mol Biomol Spectrosc.
2006 May 15;64(2):495-503.
120.
Mukherjee O, Meera P, Ghosh S, Kubendran
S, Kiran K, Manjunath KR, Subhash MN, Benegal V,
Brahmachari SK, Majumder PP, Jain S.
Evidence of linkage and association on 18p11.2 for
psychosis.
Am J Med Genet B Neuropsychiatr Genet.
2006 Aug 29; [Epub ahead of print]
121.
Simone Gupta; Siddharth S Bisht; Ritushree
Kukreti; Sanjeev Jain; Samir
K. Brahmachari.
Boolean Network Analysis of a
Neurotransmitter Signaling Pathway.
J Theor Biol. 2007 Feb 7;244(3):463-9.
Epub 2006 Aug 26.
122.
Scaria V,
Hariharan M,
Maiti
S,
Pillai
B,
Brahmachari SK.
Host-virus interaction : a new role for microRNAs.
Retrovirology. 2006 Oct 11;3(1):68.
123.
Sharma VK,
Sharma
A,
Kumar
N,
Khandelwal M,
Kumar
Mandapati K,
Horn-Saban S,
Strichman- Almashanu L,
Lancet
D,
Brahmachari SK,
Ramachandran S.
Expoldb: expression
linked polymorphism database with inbuilt tools for
analysis of expression and simple repeats.
BMC Genomics. 2006 Oct 13;7:258.
124.
Ganapathi M, Singh GP, Sandhu KS,
Brahmachari SK, Brahmachari V.
A whole genome analysis of 5' regulatory
regions of human genes for putative cis-acting
modulators of nucleosome positioning.
Gene.
2007 Apr 15;391(1-2):242-51. Epub 2007 Jan
26.
125.
Appelbe W, Auerbach AD, Becker K, Bodmer
W, Boone DJ, Boulyjenkov V, Brahmachari S, Brody
L, Brookes A, Brown AF, Byers P, Cantu JM, Cassiman JJ,
Claustres M, Concannon P, Cotton RG, den Dunnen JT,
Flicek P, Gibbs R, Hall J, Hasler J, Katz M, Kwok PY,
Laradi S, Lindblom A, Maglott D, Marsh S, Masimirembwa
CM, Minoshima S, de Ramirez AM, Pagon R, Ramesar R,
Ravine D, Richards S, Rimoin D, Ring HZ, Scriver CR,
Sherry S, Shimizu N, Stein L, Tadmouri GO, Taylor G,
Watson M.
Recommendations of the 2006 Human Variome Project
meeting
Nature Genetics. 2007
Apr; 39(4):433-6.
126.
Scaria V, Hariharan M, Brahmachari SK,
Maiti S, Pillai B.
microRNA: an
Emerging Therapeutic
ChemMedChem.
2007 Apr 5;2(6):789-792.
127.
Sharma VK, Kumar N, Brahmachari SK,
Ramachandran S.
Abundance of Dinucleotide Repeats and Gene Expression
are Inversely Correlated: a role for gene function in
addition to intron length.
Physiol Genomics. 2007 Sep
19;31(1):96-103.
128.
Prakash T, Sandhu KS, Singh NK, Bhasin Y,
Ramakrishnan C, Brahmachari SK.
Structural assessment of glycyl mutationsin invariantly
conserved motifs.
Proteins. 2007 Jul 10; 69(3):617-632.
129.
Kumar HB, Purushottam M, Kubendran S,
Gayathri P, Mukherjee O, Murthy AR, Ghosh S, Chandra P,
Reddy YC, Benegal V, Brahmachari SK, Jain S.
Serotonergic candidate genes and puerperal psychosis: an
association study.
Psychiatr Genet. 2007
Oct;17(5):253-260.
130.
Vinod Scaria, Manoj Hariharan, Beena
Pillai, Souvik Maiti and Samir K. Brahmachari.
Host–virus genome interactions: macro roles for
microRNAs.
Cellular Microbiology (2007) (Accepted for
publication).
131.
Elayanambi Sundaramoorthy, Souvik Maiti,
Samir K. Brahmachari, Shantanu Sengupta.
Predicting protein homocysteinylation targets based on
dihedral strain energy and pKa of cysteines.
Proteins (2007) (Accepted for publication).
132.
The Indian Genome Variation Consortium
(150 authors).
S.K. Brahmachari et.al.
Genetic Landscape of the People of India: a Canvas for
Disease Gene Exploration.
Nature Genetics (2007) (Revised manuscript
submitted).
TOP ^
Papers Published by Dr. Brahmachari’s
Students, Associates and Group:
(Where SKB is not an author)
1.
A new polymer supported packing material as a substitute of
Hydroxylapatite:Purification of Topoisomerases.
K.Majumder and N.Ramesh.
Chromatographia (1987) 24: 400
2.
Preparation and characterisation of a new
Matrix: Polymer supported Hydroxlapatite Substitute.
Majumder, K.
Biol.Chem.
Hoppe-Seyler (1987) 368: 760
3.
Screening of clones containing altered
DNA conformations by plasmid topoprofile shift.
N.Ramesh and R.K.Mishra.
J.Biochem.Biophys.Meth. (1991) 22: 171
4.
Hereditary ataxia with ophthalmoplegia-preliminary
observations on a Bengali family with autosomal dominant
inheritance.
Ambar Chakravarty, Angshuman Mukerjee, Somaditya
Banerjee and Quasar Saleem.
J. of
Association of Neuroscientists of Eastern India (1996)
1: 188
5.
Molecular Analysis of Friedreich’s Ataxia
locus in the Indian Population.
M.Mukerji,
S. Choudhry, Q.Saleem, M.V.Padma, M.C. Maheshwari,
S. Jain
Acta
Neurologica Scandinavica
(2000) 102(4): 227-229
6.
Sample Size considerations in genetic
polymorphism studies.
Chandrika B. Rao.
Human
Heredity
(2001) 52(4): 191-200
7.
“Spectrum of
b-thalassaemia
mutations and their association with allelic sequence
polymorphisms at the
b-globin
gene cluster in eastern Indian population”.
Ritushree Kukreti, Debasis Dash, Vineetha K E, Sanchita
Chakravarty, Swapan Kr Das, Madhusnata De, Geeta
Talukder.
American
Journal of Hematology (2002) 70(4):269-77.
8.
Origin and instability of GAA repeats:
insights from Alu elements.
Chauhan C, Dash D, Grover D, Rajamani J, Mukerji M.
J Biomol
Struct Dyn. 2002 Oct; 20(2):253-63.
9.
Spectrum of beta-thalassemia mutations
and their association with allelic sequence
polymorphisms at the beta-globin gene cluster in an
Eastern Indian population.
Kukreti R, Dash D, E VK, Chakravarty S,
Das SK, De M, Talukder G
Am J
Hematol. 2002 Aug; 70(4):269-77.
10.
In silico characterization of the INO80
subfamily of SWI2/SNF2 chromatin remodeling proteins.
Bakshi R, Prakash T, Dash D, Brahmachari V.
Biochem
Biophys Res Commun. 2004 Jul 16; 320(1):197-2.
11.
Comparative analysis of protein
unfoldedness in human housekeeping and non-housekeeping
proteins.
Pandey N, Ganapathi M, Kumar
K, Dasgupta D, Sutar SD,
Dash D.
Bioinformatics.
2004 Nov 22; 20(17):2904-10
12.
SMARCA2 and THAP11: potential candidates
for polyglutamine disorders as evidenced from
polymorphism and protein-folding simulation studies.
Pandey N,
Mittal U,
Srivastava AK,
Mukerji M.
J Hum Genet.
2004;
49(11):596-602. Epub 2004 Sep 10.
13.
ArrayD: a general purpose
software for microarray design.
Sharma A, Srivastava GP, Sharma VK, Ramachandran S.
BMC Bioinformatics.
2004 Oct 2;5:142.
14.
Founder Haplotype for
Machado-Joseph Disease in the Indian Population: Novel
Insights from History and Polymorphism Studies.
Uma
Mittal; Achal K. Srivastava; Satish Jain; Sanjeev Jain;
Mitali Mukerji.
Arch Neurol
2005; 62 637-640.
15.
Post-zygotic de novo
trinucleotide repeat expansion at spinocerebellar ataxia
type 7 locus: evidence from an Indian family.
Mittal U, Roy S, Jain S, Srivastava AK, Mukerji M.
J Hum Genet.
2005; 50(3):155-7. Epub
2005 Mar 5.
16.
Evidence of a Common
Founder for SCA12 in the Indian Population.
S. Bahl K. Virdi, U. Mittal, M. P. Sachdeva, A. K. Kalla,
S. E. Holmes, E. O'Hearn, R. L. Margolis, S. Jain, A. K.
Srivastava and M. Mukerji.
Ann Hum Genet. 2005 Sep; 69(Pt 5):528-34.
17.
Insights into the
mutational history and prevalence of SCA1 in the Indian
population through anchored polymorphisms.
Mittal U,
Sharma S,
Chopra R,
Dheeraj K,
Pal PK,
Srivastava AK,
Mukerji M.
Hum Genet. 2005 Nov; 118(1):107-14. Epub.
2005 Oct 28.
18.
SPAAN: a software program
for prediction of adhesins and adhesin-like proteins
using neural networks.
Sachdeva G, Kumar K, Jain P, Ramachandran S.
Bioinformatics. 2005 Feb 15;21(4):483-91. Epub 2004
Sep 16.
19.
Intrinsic
unstructuredness and abundance of PEST motifs in
eukaryotic proteomes.
Singh GP, Ganapathi M,
Sandhu KS,
Dash D.
Proteins. 2006 Feb 1; 62(2):309-15.
20.
Simple sequence proteins
in prokaryotic proteomes.
Subramanyam MB, Gnanamani M, Ramachandran S.
BMC Genomics. 2006 Jun 8;7:141.
21.
Conformational
flexibility may explain multiple cellular roles of PEST
motifs.
Sandhu KS, Dash D.
Proteins. 2006 Jun 1; 63(4):727-32.
22.
DyNAVacS: an integrative
tool for optimized DNA vaccine design.
Harish N, Gupta R, Agarwal P, Scaria V, Pillai B.
Nucleic Acids Res. 2006 Jul 1;34(Web Server issue):W264-6.
23.
Quadfinder: server for
identification and analysis of quadruplex-forming motifs
in nucleotide sequences.
Scaria V, Hariharan M, Arora A, Maiti S.
Nucleic Acids Res. 2006 Jul 1;34(Web Server
issue):W683-5.
24.
Bhatnagar P, Guleria R, Kukreti R.
Pharmacogenomics of beta2-agonist: key focus on
signaling pathways.
Pharmacogenomics. 2006 Sep;7(6):919-33. Review.
25.
Ravi Shankar, Amit
Chaurasia, Biswaroop Ghosh, Dmitry Chekmenev, Evgeny
Cheremushkin, Alexander Kel, Mitali Mukerji.
Non-random genomic divergence in repetitive sequences of
human and chimpanzee in genes of diVerent functional
categories.
Mol Genet Genomics (2007) 277:441–455.
26.
Singh GP, Ganapathi M,
Dash D.
Role of intrinsic disorder in transient interactions of
hub proteins.
Proteins. 2007 Mar 1;66(4):761-5.
27.
Sandhu KS, Dash D.
Dynamic alpha-helices: conformations that do not
conform.
Proteins. 2007 Jul 1;68(1):109-22.
28.
Singh GP, Dash D.
Intrinsic disorder in yeast transcriptional regulatory
network.
Proteins. 2007 Aug 15;68(3):602-5.
TOP ^
Patents
|
S. No. |
Title |
Inventors |
Country
(Publicatoin Date) |
Filing Date |
Grant Date |
Patent No. |
|
1.
|
Computational method for identifying adhesin and
adhesin- like proteins of therapeutic potential |
Sachdeva Gaurav, Kumar Kaushal, Preti Jain,
Brahmachari SK, Ramachandran S |
India |
29-May-06 |
|
|
|
US |
20-Jul-04 |
|
|
|
WO |
07-Feb-05 |
|
|
|
2.
|
A
computer based method for identifying conserved
invariant peptide motifs |
Brahmachari SK, Dash D |
BR
(14-Jan-03) |
30-Sep-02 |
|
|
|
CA
(11-Oct-01) |
07-Dec-01 |
|
|
|
CN |
26-Nov-02 |
20-Jul-05 |
218305 |
|
CZ
(15-May-02) |
04-Jan-02 |
|
| |