Abhay Sharma

Sr. Scientist
Systems biology

Abhay Sharma is interested in applying systems biology approach in neuropsychiatric drug discovery and in understanding transgenerational epigenetic inheritance. His lab has developed a Drosophila model for identifying compounds with therapeutic potential in neuropsychiatric disorders. The model is presently being implemented in a drug discovery project. Besides, his lab provided the first evidence of transgenerational spermatogenic inheritance of acquired characteristics. In this study, drug-induced transcriptomic alteration in fly CNS was found to be inherited. He has recently proposed a novel concept of transgenerational systems biology.

Using high-throughput gene expression profiling as a tool, he is interested in identifying:

  • Novel therapeutic potential of existing compounds in neuropsychiatric disorders
  • Gene networks underlying metabolic perturbations in Drosophila and its transgenerational inheritance

Selected Publications:

Contact Information

Abhay Sharma
Office:
Room No. 022
CSIR-IGIB, 
Sukhdev Vihar, 
Mathura Road, 
New Delhi - 110 025
Tel: 91-11-29879122

e-mail:
abhaysharma@igib.res.in