M. A. Q. Pasha

High Altitude Disorders

M.A.Q. Pasha is interested in the physiological changes and genetic susceptibility associated with acclimatization to high altitude. He has identified several genetic polymorphisms in the Indian population that are linked to the ability to adapt to high-altitude. A parallel interest is the involvement of these genes and pathways in Chronic Obstructive Pulmonary Disorder.

Selected Publications:

  • COX2 and p53 risk-alleles coexist in COPD. Arif, E., Vibhuti, A., Deepak, D., Singh, B., Siddiqui, M. S., and Pasha, M. A. Clin.Chim.Acta. 2008. 397[1-2], 48-50.
  • The genetic aspects of pre-eclampsia: achievements and limitations. Nejatizadeh, A., Stobdan, T., Malhotra, N., and Pasha, M. A. Biochem.Genet. 2008. 46[7-8], 451-479.
  • Endothelial nitric oxide synthase gene haplotypes and circulating nitric oxide levels significantly associate with risk of essential hypertension. Nejatizadeh, A., Kumar, R., Stobdan, T., Goyal, A. K., Sikdar, S., Gupta, M., Javed, S., and Pasha, M. A. Free Radic.Biol.Med. 2008. 44[11], 1912-1918.
  • Endothelial nitric oxide synthase gene variants contribute to oxidative stress in COPD. Arif, E., Ahsan, A., Vibhuti, A., Rajput, C., Deepak, D., Athar, M., Singh, B., and Pasha, M. A. Biochem.Biophys.Res.Commun. 2007. 361[1], 182-188.
  • cDNA cloning, gene organization and variant specific expression of HIF-1 alpha in high altitude yak (Bos grunniens). Dolt, K. S., Mishra, M. K., Karar, J., Baig, M. A., Ahmed, Z., and Pasha, M. A. Gene. 2007. 386[1-2], 73-80.

Contact Information

M. A. Q. Pasha
Lab #510,
Institute of Genomics and Integrative Biology, Mall Road,
Phone no:+91-11-2766 6156/7 extn:148
Fax no: 011-2766 7471
e-mail: qpasha@igib.in

Mailing Address
Lab 510
Institute of Genomics and Integrative Biology, Mall Road
New Delhi- 110 007