Mitali Mukerji

Genome variation and human disease susceptibility

Mitali Mukerji’s research is in the broad area of genome variation and it’s effect on human phenotypes and susceptibility to diseases. Her research interests include:

Application of polymorphisms in mapping mutations and disease origins in SCAs
Ayurgenomics: exploring the principles of predictive medicine in Ayurveda
Alu elements in genome organization and function

She has been actively involved in the Indian Genome Variation Consortium. She is combining genomics with phenotyping principles of Ayurveda and objective parameters of modern medicine for identifying molecular endophenotypes. Her group is studying the role of Alu elements in evolution of novel regulatory networks through functional genomics approaches.

Selected Publications:

  • Heat shock factor binding in Alurepeats expands its involvement in stress through an antisense mechanism.Pandey R, Mandal AK, Jha V, Mukerji M. Genome Biol. 2011 Nov 23;12(11):R117.


  • Ayurgenomics: a new way of threading molecularvariability for stratified medicine.Sethi TP, Prasher B, Mukerji M. ACS Chem Biol. 2011 Sep 16;6(9):875-80.


  • Recent admixture in anIndian population of African ancestry.Narang A, Jha P, Rawat V, Mukhopadhyay A, Dash D;Indian Genome Variation Consortium, Basu A, Mukerji M. Am J Hum Genet. 2011 Jul 15;89(1):111-20.


  • EGLN1 involvement inhigh-altitude adaptation revealed through genetic analysis of extremeconstitution types defined in Ayurveda. Aggarwal S, Negi S, Jha P, Singh PK, Stobdan T, Pasha MA, Ghosh S, Agrawal A; Indian Genome Variation Consortium, Prasher B, Mukerji M. Proc Natl Acad Sci U S A. 2010 Nov2;107(44):18961-6.


  • Whole genome expression and biochemical correlates ofextreme constitutional types defined in Ayurveda.Prasher B, Negi S, Aggarwal S, Mandal AK, Sethi TP, Deshmukh SR, Purohit SG,Sengupta S, Khanna S, Mohammad F, Garg G, Brahmachari SK; Indian Genome VariationConsortium, Mukerji M. J Transl Med. 2008 Sep 9;6:48.

Contact Information

Mitali Mukerji
Office:
Room No. 607
Institute of Genomics and Integrative Biology, Mall Road, Delhi.
Phone no:+91-11-2766 6156/7
Extn: 121

Room No. 302,
CSIR-IGIB,
Sukhdev Vihar,
Mathura Road,
New Delhi - 110 020
Tel: 91-11-29879 302

Fax no: 011-2766 7471
e-mail: mitali@igib.res.in

Mailing Address
Lab 607,
Institute of Genomics and Integrative Biology, Mall Road
New Delhi- 110 007