S. Ramachandran

Senior Principal Scientist
Informatics and Big Data

Integrative Bioinformatics, Data analytics, Selected Experimental validation.

His group is interested in:
  • Annotating adhesion virulence factors using artificial intelligence
  • The genetic and metabolic network of M. tuberculosis has propensity to confer transition from active to persistent state
  • Chemical descriptors of inhibitors for Dihydrodipicolinate synthase of M. tuberculosis

Seven genes AGER, TNFRSF11B, CRK, PON1, ADIPOQ, CRP and NOS3 are associated with all 5 complications, namely Atherosclerosis, Cardiovascular, Nephropathy, Neuropathy and Retinopathy. VEGFA is associated with several complications of T2DM. A few genes ACE2, ADCYAP1, HDAC4, NCF1, NFE2L2, OSM, SMAD1, TGFB1, BDNF, SYVN1, TXNIP, CD36, CYP2J2, NLRP3 with details of protective role are catalogued.

Selected Publications:

Contact Information

S. Ramachandran
Room No. 130
Sukhdev Vihar, 
Mathura Road, 
New Delhi - 110 025

Tel: 91-11-29879130

e-mail: ramu@igib.res.in

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